Spots Global Cancer Trial Database for Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)
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Trial Identification
Brief Title: Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)
Official Title: A Phase II, Open-Label, Multicenter Trial to Investigate the Clinical Activity and Safety of Avelumab (MSB0010718C) in Subjects With Merkel Cell Carcinoma
Study ID: NCT02155647
Conditions
Interventions
Study Description
Brief Summary: This is a multicenter, international, single-arm, open-label, Phase 2 trial to evaluate the efficacy and safety of avelumab in participants with metastatic Merkel cell carcinoma (MCC).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
UCLA Medical Center, Los Angeles, California, United States
The Angeles Clinic and Research Institute - West LA, Los Angeles, California, United States
University of Colorado, Aurora, Colorado, United States
H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa, Florida, United States
National Cancer Institute, Bethesda, Maryland, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Mount Sinai, New York, New York, United States
Peggy & Charles Stephenson Oklahoma Cancer Center, Oklahoma City, Oklahoma, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
University of Washington - Seattle Cancer Care Alliance, Seattle, Washington, United States
Port Macquarie Base Hospital, Port Macquarie, New South Wales, Australia
Royal North Shore Hospital, St Leonards, New South Wales, Australia
Tasman Oncology Research Ltd, Southport, Queensland, Australia
Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
St John of God Subiaco Hospital, Perth, Western Australia, Australia
CHU Nice - Hopital de l Archet 2, Nice cedex 3, Alpes Maritimes, France
H么pital de la Timone, Marseille cedex 05, Bouches-du-Rh么ne, France
CHU Besan莽on - H么pital Jean Minjoz, Besan莽on Cedex, Doubs, France
CHU Nantes - H么tel Dieu, Nantes Cedex 1, Loire Atlantique, France
Hopital Claude Huriez - CHU Lille, Lille cedex, Nord, France
H么pital Saint-Louis, Paris Cedex 10, Paris, France
Centre Hospitalier Lyon Sud, Pierre Benite cedex, Rhone, France
Institut Gustave Roussy, Villejuif cedex, Val De Marne, France
Groupe Hospitalier Saint Andr茅 - H么pital Saint Andr茅, Bordeaux, , France
H么pital Ambroise Par茅 - Boulogne-Billancourt, Boulogne Billancourt, , France
CHU Tours - H么pital Trousseau, Chambray Les Tours, , France
CHU de Dijon - Hopital du Bocage, Dijon, , France
CHU de Grenoble - H么pital A Michallon, Grenoble, , France
CHU de Limoges - H么pital Dupuytren, Limoges, , France
Universitaetsklinikum Heidelberg, Heidelberg, Baden Wuerttemberg, Germany
Klinikum der Johann Wolfgang Goethe-Universitaet, Frankfurt, Hessen, Germany
St. Josef-Hospital Universitaetsklinikum, Bochum, Nordrhein Westfalen, Germany
Universitaetsklinikum Essen, Essen, Nordrhein Westfalen, Germany
Universitaetsklinikum Koeln, Koeln, Nordrhein Westfalen, Germany
Fachklinik Hornheide, Muenster, Nordrhein Westfalen, Germany
Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Sachsen, Germany
Universitaetsklinikum Schleswig-Holstein - Klinik fuer Allgemeine Innere Medizin, Kiel, Schleswig Holstein, Germany
Universitaetsklinikum Schleswig Holstein - Campus Luebeck, Luebeck, Schleswig Holstein, Germany
Helios Klinikum Erfurt, Erfurt, Thueringen, Germany
Charite Universitaetsmedizin Berlin - Campus Charite Mitte, Berlin, , Germany
Fondazione del Piemonte per l'Oncologia IRCC Candiolo, Candiolo, Torino, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, , Italy
IEO Istituto Europeo di Oncologia, Milano, , Italy
Istituto Nazionale Tumori Fondazione G.Pascale, Napoli, , Italy
IOV - Istituto Oncologico Veneto IRCCS, Padova, , Italy
Azienda Ospedaliera di Perugia Ospedale S. Maria della Misericordia, Perugia, , Italy
Arcispedale S. Maria Nuova Azienda Ospedaliera di Reggio Emilia, Reggio Emilia, , Italy
Istituto Nazionale Tumori Regina Elena IRCCS, Roma, , Italy
A.O.U. Senese Policlinico Santa Maria alle Scotte, Siena, , Italy
Shizuoka Cancer Center, Shizuoka, Shizuoka-Ken, Japan
National Cancer Center Hospital, Chuo-ku, , Japan
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Hospital Clinic i Provincial de Barcelona, Barcelona, , Spain
Hospital General Universitario Gregorio Mara帽on, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital General Universitario de Valencia, Valencia, , Spain
Contact Details
Name: Medical Responsible
Affiliation: Merck KGaA, Darmstadt, Germany
Role: STUDY_DIRECTOR
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