Spots Global Cancer Trial Database for ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
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Trial Identification
Brief Title: ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Official Title: A Randomized, Partially Blinded, Phase II Study to Assess the Safety, Tolerability and Efficacy of ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Study ID: NCT00071188
Conditions
Study Description
Brief Summary: The purpose of the run-in phase of this study is to determine the appropriate and tolerable dose of ZD6474 (200mg or 300mg) to be administered in combination with paclitaxel and carboplatin in subjects with previously untreated locally advanced or metastatic NSCLC. This phase of the trial is closed to enrollment. The purpose of the randomized phase of this study is to determine the efficacy of ZD6474 alone versus that of ZD6474 in combination with paclitaxel and carboplatin versus that of paclitaxel and carboplatin alone in subjects with previously untreated locally advanced or metastatic NSCLC. This phase of the trial is closed to enrollment.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Concord, California, United States
Research Site, Los Angeles, California, United States
Research Site, Chicago, Illinois, United States
Research Site, Boston, Massachusetts, United States
Research Site, St. Louis, Missouri, United States
Research Site, Providence, Rhode Island, United States
Research Site, Nashville, Tennessee, United States
Research Site, Austin, Texas, United States
Research Site, Houston, Texas, United States
Research Site, Lubbock, Texas, United States
Research Site, Norfolk, Virginia, United States
Research Site, Seattle, Washington, United States
Research Site, Helsinki, , Finland
Research Site, Turku, , Finland
Research Site, Besancon, , France
Research Site, Lille, , France
Research Site, Strasbourg, , France
Research Site, Essen, , Germany
Research Site, Frankfurt, , Germany
Research Site, Mainz, , Germany
Research Site, Ulm, , Germany
Research Site, Pune, , India
Research Site, Milano, , Italy
Research Site, Orbassano, , Italy
Research Site, Cape Town, , South Africa
Research Site, Johannesburg, , South Africa
Research Site, Panorama, , South Africa
Research Site, Parkland, , South Africa
Research Site, Pretoria, , South Africa
Research Site, Barcelona, , Spain
Research Site, Madrid, , Spain
Research Site, Malaga, , Spain
Research Site, Pamplona, , Spain
Research Site, Chiang mai, , Thailand
Contact Details
Name: Clinical Sciences & Operations
Affiliation: Sanofi
Role: STUDY_DIRECTOR
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