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Spots Global Cancer Trial Database for A Study of the Efficacy and Safety of Alectinib in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer

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Trial Identification

Brief Title: A Study of the Efficacy and Safety of Alectinib in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer

Official Title: An Open-Label, Multicenter, Single-Arm, Phase II Study to Assess the Efficacy and Safety of Alectinib in Patients With ALK-Rearranged Non-Small Cell Lung Cancer After Disease Progression on Prior ALK Inhibitor Therapy

Study ID: NCT03155009

Interventions

Alectinib

Study Description

Brief Summary: This study will evaluate the efficacy and safety of alectinib, in selected participants, with anaplastic lymphoma kinase-rearranged (ALK-rearranged) non-small cell lung cancer (NSCLC), after disease progression on prior treatment strategy with crizotinib, as only ALK inhibitor, and eventually chemotherapy treatment(s).

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

CHU Angers, Angers, , France

Hopital Jean Minjoz; Pneumologie, Besancon, , France

Hopital Augustin Morvan; Oncologie Thoracique, Brest, , France

Centre Francois Baclesse; Comite 3, Caen, , France

Centre Hospitalier Intercommunal; Service de Pneumologie, Creteil, , France

Hôpital Nord Michallon; Pneumologie, La Tronche, , France

CHRU Lille Service de Pneumologie et Oncologie Thoracique, Lille, , France

Hôpital Nord - AP-HM Marseille#, Marseille, , France

Hopital Emile Muller;Pneumologie, Mulhouse, , France

Institut Curie, Paris, , France

Hopital Tenon;Pneumologie, Paris, , France

CHU de Bordeaux, Pessac, , France

Hopital de Pontchaillou; Service de Pneumologie, Rennes, , France

CHU de Rouen - Hôpital Charles Nicolle, Rouen, , France

CHU de Toulouse - Hôpital Larrey; Service de pneumologie et oncologie pneumologique, Toulouse cedex 9, , France

Hopital Robert Schuman; Pneumologie, Vantoux, , France

Contact Details

Name: Clinical Trials

Affiliation: Hoffmann-La Roche

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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