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Brief Title: A Study of the Efficacy and Safety of Alectinib in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer
Official Title: An Open-Label, Multicenter, Single-Arm, Phase II Study to Assess the Efficacy and Safety of Alectinib in Patients With ALK-Rearranged Non-Small Cell Lung Cancer After Disease Progression on Prior ALK Inhibitor Therapy
Study ID: NCT03155009
Brief Summary: This study will evaluate the efficacy and safety of alectinib, in selected participants, with anaplastic lymphoma kinase-rearranged (ALK-rearranged) non-small cell lung cancer (NSCLC), after disease progression on prior treatment strategy with crizotinib, as only ALK inhibitor, and eventually chemotherapy treatment(s).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
CHU Angers, Angers, , France
Hopital Jean Minjoz; Pneumologie, Besancon, , France
Hopital Augustin Morvan; Oncologie Thoracique, Brest, , France
Centre Francois Baclesse; Comite 3, Caen, , France
Centre Hospitalier Intercommunal; Service de Pneumologie, Creteil, , France
Hôpital Nord Michallon; Pneumologie, La Tronche, , France
CHRU Lille Service de Pneumologie et Oncologie Thoracique, Lille, , France
Hôpital Nord - AP-HM Marseille#, Marseille, , France
Hopital Emile Muller;Pneumologie, Mulhouse, , France
Institut Curie, Paris, , France
Hopital Tenon;Pneumologie, Paris, , France
CHU de Bordeaux, Pessac, , France
Hopital de Pontchaillou; Service de Pneumologie, Rennes, , France
CHU de Rouen - Hôpital Charles Nicolle, Rouen, , France
CHU de Toulouse - Hôpital Larrey; Service de pneumologie et oncologie pneumologique, Toulouse cedex 9, , France
Hopital Robert Schuman; Pneumologie, Vantoux, , France
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR