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Brief Title: Evaluation of FKB238 and Avastin in Patients With Advanced/Recurrent Non-squamous Non-small Cell Lung Cancer
Official Title: A Randomised, Parallel, Double Blinded Study to Compare the Efficacy and Safety of FKB238 to Avastin® In 1st Line Treatment for Patients With Advanced/Recurrent Non Squamous NSCLC in Combination of Paclitaxel and Carboplatin
Study ID: NCT02810457
Brief Summary: The purpose of this research study is to compare the effectiveness and safety of FKB238 against Avastin® in men and women with advanced/recurrent non squamous non-small cell lung cancer
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site 7814 - Compassionate Care Research Group, Fountain Valley, California, United States
Research Site 7811 - Innovative Clinical Research Institute, Whittier, California, United States
Research Site 7803 - 21st Century Oncology, Jacksonville, Florida, United States
Research Site 7812 - Joliet Oncology-Hematology Associates, Ltd., Joliet, Illinois, United States
Research Site 7810 - Edward H. Kaplan, MD and Associates, Skokie, Illinois, United States
Research Site 7813 - Trinity Cancer Care Center, Minot, North Dakota, United States
Research Site 7805 - Hematology & Oncology Associates, Inc., Canton, Ohio, United States
Research Site 7801 - Gabrail Cancer Center, Canton, Ohio, United States
Research Site 7804 - Tri-County Hematology & Oncology Associates, Inc., Massillon, Ohio, United States
Research Site 7809 - Millennium Oncology, Houston, Texas, United States
Research Site 7806 - Vista Oncology Inc. PS, Olympia, Washington, United States
Research Site 8507, Brest, Brestskaya Voblasts, Belarus
Research Site 8505, Grodno, Hrodzenskaya Voblasts, Belarus
Research Site 8502, Mogilev, Mahilyowskaya Voblasts, Belarus
Research Site 8501, Lesnoy, Minskaya Voblasts, Belarus
Research Site 8504, Minsk, Minskaya Voblasts, Belarus
Research Site 8506, Vitebsk, Vitsyebskaya Voblasts, Belarus
Research Site 8605, Tuzla, Tuzlanski Kanton, Bosnia and Herzegovina
Research Site 8606, Banja Luka, , Bosnia and Herzegovina
Research Site 8602, Mostar, , Bosnia and Herzegovina
Research Site 8601, Sarajevo, , Bosnia and Herzegovina
Research Site 8603, Sarajevo, , Bosnia and Herzegovina
Research Site 8604, Zenica, , Bosnia and Herzegovina
Research Site 0905, Sofia, Dobrich, Bulgaria
Research Site 0904, Varna, , Bulgaria
Research Site 1802, Zagreb, Grad Zagreb, Croatia
Research Site 1803, Zagreb, Grad Zagreb, Croatia
Research Site 1801, Osijek, Osjecko-baranjska Županija, Croatia
Research Site 2504, Bat'umi, Ajaria, Georgia
Research Site 2507, Kutaisi, Imereti, Georgia
Research Site 2503, Tbilisi, , Georgia
Research Site 2505, Tbilisi, , Georgia
Research Site 2508, Tbilisi, , Georgia
Research Site 2605, Würselen, Nordrhein-Westfalen, Germany
Research Site 2603, Kiel, Schleswig-Holstein, Germany
Research Site 2604, Hamburg, , Germany
Research Site 3004, Athens, , Greece
Research Site 3003, Thessaloniki, , Greece
Research Site 3005, Thessaloníki, , Greece
Research Site 3303, Gyula, Békés, Hungary
Research Site 3302, Deszk, Csongrád, Hungary
Research Site 3301, Mátraháza, Heves, Hungary
Research Site 3305, Budapest, , Hungary
Research Site 3304, Budapest, , Hungary
Research Site 3306, Zalaegerszeg, , Hungary
Research Site 4107, Catania, , Italy
Research Site 4106, Piacenza, , Italy
Research Site 4301, Fukuyama-shi, Hiroshima, Japan
Research Site 4304, Kumamoto-shi, Kumamoto, Japan
Research Site 4303, Sasebo-shi, Nagasaki, Japan
Research Site 6005, Busan, Busan Gwang'yeogsi, Korea, Republic of
Research Site 6004, Suwon-si, Gyeonggido, Korea, Republic of
Research Site 6002, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Research Site 6003, Ulsan, Ulsan Gwang'yeogsi, Korea, Republic of
Research Site 5402, Arequipa, , Peru
Research Site 5404, Arequipa, , Peru
Research Site 5401, Lima, , Peru
Research Site 5405, Lima, , Peru
Research Site 5505, Cebu City, Cebu, Philippines
Research Site 5504, Makati City, National Capital Region, Philippines
Research Site 5501, Manila, National Capital Region, Philippines
Research Site 5502, Manila, National Capital Region, Philippines
Research Site 5506, Manila, National Capital Region, Philippines
Research Site 5503, Quezon, , Philippines
Research Site 5705, Toruniak, Kujawsko-pomorskie, Poland
Research Site 5708, Lodz, Lódzkie, Poland
Research Site 5701, Krakow, Malopolskie, Poland
Research Site 5702, Elblag, Warminsko-mazurskie, Poland
Research Site 5706, Olsztyn, Warminsko-mazurskie, Poland
Research Site 5711, Brzozów, , Poland
Research Site 5703, Nowy Sacz, , Poland
Research Site 6105, Cluj-Napoca, Cluj, Romania
Research Site 6106, Cluj-Napoca, Cluj, Romania
Research Site 6108, Floreşti, Cluj, Romania
Research Site 6101, Baia Mare, , Romania
Research Site 6102, Constanta, , Romania
Research Site 6103, Craiova, , Romania
Research Site 6107, Iasi, , Romania
Research Site 6209, Arkhangelsk, Arkhangel'skaya Oblast', Russian Federation
Research Site 6220, Ufa, Bashkortostan, Respublika, Russian Federation
Research Site 6221, Belgorod, Belgorodskaya Oblast', Russian Federation
Research Site 6211, Chelyabinsk, Chelyabinskaya Oblast', Russian Federation
Research Site 6217, Kuzmolovskiy, Leningradskaya Oblast', Russian Federation
Research Site 6219, Saransk, Mordoviya, Respublika, Russian Federation
Research Site 6225, Moscow, Moskva, Russian Federation
Research Site 6203, Moscow, Moskva, Russian Federation
Research Site 6230, Novgorod, Nizhegorodskaya Oblast', Russian Federation
Research Site 6214, Novosibirsk, Novosibirskaya Oblast', Russian Federation
Research Site 6213, Novosibirsk, Novosibirskaya Oblast', Russian Federation
Research Site 6215, Omsk, Omskaya Oblast', Russian Federation
Research Site 6224, Omsk, Omskaya Oblast', Russian Federation
Research Site 6208, Orenburg, Orenburgskaya Oblast', Russian Federation
Research Site 6223, Rostov-on-Don, Rostovskaya Oblast', Russian Federation
Research Site 6205, Ryazan', Ryazanskaya Oblast', Russian Federation
Research Site 6234, Samara, Samarskaya Oblast', Russian Federation
Research Site 6235, Saint Petersburg, Sankt-Peterburg, Russian Federation
Research Site 6212, Saint Petersburg, Sankt-Peterburg, Russian Federation
Research Site 6216, Saint Petersburg, Sankt-Peterburg, Russian Federation
Research Site 6201, Saint Petersburg, Sankt-Peterburg, Russian Federation
Research Site 6202, Sankt Petersburg, Sankt-Peterburg, Russian Federation
Research Site 6210, Sankt Petersburg, Sankt-Peterburg, Russian Federation
Research Site 6229, Izhevsk, Udmurtskaya Respublika, Russian Federation
Research Site 6228, Kursk, , Russian Federation
Research Site 6207, Magnitogorsk, , Russian Federation
Research Site 6222, Saint Petersburg, , Russian Federation
Research Site 6401, Sremska Kamenica, Vojvodina, Serbia
Research Site 6402, Belgrade, , Serbia
Research Site 6403, Belgrade, , Serbia
Research Site 6404, Belgrade, , Serbia
Research Site 6405, Belgrade, , Serbia
Research Site 6406, Kragujevac, Šumadijski Okrug, Serbia
Research Site 7004, A Coruna, A Coruña, Spain
Research Site 7002, Castellón De La Plana, Castellon, Spain
Research Site 7005, Cordoba, Córdoba, Spain
Research Site 7009, Jaen, Jaén, Spain
Research Site 7001, Burgos, , Spain
Research Site 7007, Madrid, , Spain
Research Site 7008, Murcia, , Spain
Research Site 7003, Murcia, , Spain
Research Site 7402, New Taipei City, Taipei, Taiwan
Research Site 7404, Douliu, Yunlin, Taiwan
Research Site 7403, Changhua, , Taiwan
Research Site 7401, Taipei, , Taiwan
Research Site 7506, Bangkok, Krung Thep Maha Nakhon, Thailand
Research Site 7501, Hat Yai, Songkhla, Thailand
Research Site 7504, Bangkok, , Thailand
Research Site 7507, Chiang Mai, , Thailand
Research Site 7505, Chiang Rai, , Thailand
Research Site 7503, Khon Kaen, , Thailand
Research Site 7502, Udon Thani, , Thailand
Research Site 7607, Ankara, , Turkey
Research Site 7605, İzmir, , Turkey
Research Site 7601, Izmir, , Turkey
Research Site 7606, Malatya, , Turkey
Research Site 7702, Chernivtsi, Chernivets'ka Oblast', Ukraine
Research Site 7705, Kharkiv, Kharkivs'ka Oblast', Ukraine
Research Site 7706, Odesa, Odes'ka Oblast', Ukraine
Research Site 7713, Lutsk, Volyns'ka Oblast', Ukraine
Research Site 7707, Uzhgorod, Zakarpats'ka Oblast', Ukraine
Research Site 7709, Dnipropetrovs'k, , Ukraine
Research Site 7701, Ivano-Frankivs'k, , Ukraine
Research Site 7708, Kryvyi Rih, , Ukraine
Research Site 7704, Kyiv, , Ukraine
Research Site 7710, Sumy, , Ukraine
Research Site 8401, Hanoi, Ha Noi, Thu Do, Vietnam
Research Site 8402, Hanoi, Ha Noi, Thu Do, Vietnam
Research Site 8405, Hanoi, Ha Noi, Thu Do, Vietnam
Name: Centus Biotherapeutics Limited
Affiliation: Centus Biotherapeutics Limited
Role: STUDY_DIRECTOR