Spots Global Cancer Trial Database for Erlotinib (Tarceva) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With EGFR Positive NSCLC
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Trial Identification
Brief Title: Erlotinib (Tarceva) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With EGFR Positive NSCLC
Official Title: A Phase 2 Randomized Study of Tarceva (Erlotinib) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With Newly Diagnosed Advanced Non-small Cell Lung Cancer Who Have Tumors With EGFR Protein Overexpression and/or Increased EGFR Gene Copy Numbers
Study ID: NCT00294762
Conditions
Study Description
Brief Summary: This will be the first prospective study where patients will be selected on the basis of two measures of the epidermal growth factor receptor (EGFR) pathway. The study will assess prospectively the efficacy of erlotinib as a single agent or intercalated with chemotherapy in highly selected patients with EGFR overexpression and/or EGFR amplification.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Central Hematology Oncology Medical Group Inc., Alhambra, California, United States
Comprehensive Blood and Cancer Center(Part of TORI network), Bakersfield, California, United States
Bay Area Cancer Research Group, Concord, California, United States
Virginia K. Crosson Cancer Center, Fullerton, California, United States
Pacific Shores Medical Group, Long Beach, California, United States
UCLA Medical Center, Los Angeles, California, United States
North Valley Hematology/Oncology Medical GroupThe Thomas and Dorothy Leavey Cancer Center, Northridge, California, United States
Ventura County Hematology-Oncology Specialists, Oxnard, California, United States
Wilshire Oncology Medical GroupThe Robert and Beverly Lewis Family Cancer Care Center, Pomona, California, United States
Cancer Care Associates Medical Group, Inc., Redondo Beach, California, United States
Sansum Santa Barbara Medical Foundation Clinic, Santa Barbara, California, United States
Santa Barbara Hematology Oncology Medical Group, Inc., Santa Barbara, California, United States
University of Colorado Cancer Center, Aurora, Colorado, United States
Rocky Mountain Cancer CenterResearch Department, Denver, Colorado, United States
Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut, United States
MD Anderson Cancer Ctr - Orlando, Orlando, Florida, United States
Gulfcoast Oncology Associates, Tampa, Florida, United States
Suburban Hematology-Oncology Associates, Lawrenceville, Georgia, United States
Central Georgia Cancer Care, P.C., Macon, Georgia, United States
Rush-Presbyterian-St.Luke's Med Ctr, Chicago, Illinois, United States
University of Chicago Medical Center, Chicago, Illinois, United States
Norton Healthcare, Inc., Louisville, Kentucky, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
Univ. of Minnesota Cancer Center, Minneapolis, Minnesota, United States
Hematology Oncology Centers of Northern Rockies Research, Billings, Montana, United States
Alegent Healthcare, Omaha, Nebraska, United States
Comprehensive Cancer Centers of Nevada, Henderson, Nevada, United States
Hematology-Oncology Associates, SJ, PA - Virtua Health, Mount Holly, New Jersey, United States
Providence Portland Medical Center, Portland, Oregon, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Pottsville Cancer Clinic, Pottsville, Pennsylvania, United States
Boston Baskin Cancer Groupd/b/a U. of Tennessee Cancer Inst., Memphis, Tennessee, United States
The West Cancer Clinic, Memphis, Tennessee, United States
ACORN, Memphis, Tennessee, United States
University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States
Fletcher Allen Health Care, Burlington, Vermont, United States
Cancer Specialists of Tidewater, Ltd., Chesapeake, Virginia, United States
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
Birmingham Heartlands Hospital, Birmingham, , United Kingdom
CR UK, Cambridge, , United Kingdom
Peterborough District Hospital, Cambridge, , United Kingdom
Beatson Oncology Centre, Glasgow, , United Kingdom
Mount Vernon Hospital, Middlesex, , United Kingdom
Contact Details
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