Spots Global Cancer Trial Database for French National Observatory of the Patients With Non-small Cell Lung (NSCLC) and Molecular Testings
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Trial Identification
Brief Title: French National Observatory of the Patients With Non-small Cell Lung (NSCLC) and Molecular Testings
Official Title: French National Observatory of the Patients With Non-small Cell Lung (NSCLC) Benefiting From a Molecular Test on the Hospital Platforms of Molecular Genetics.
Study ID: NCT01700582
Interventions
Study Description
Brief Summary: The French National Cancer Institute (INCa) support a 28 hospital platforms network for molecular testing of cancer patients. These platforms routinely assess a panel of biomarkers in order to speed up access of French cancer patients to targeted therapies (commercially available or through clinical trials). The objective of the BIOMARKERS-France study is to describe the epidemiological, clinical and molecular characteristics of these patients and their tumors and to assess the impact of these analyzes on their treatment (ie bio-guided therapy) as well as outcomes (response rate, progression free and overall survival).
Detailed Description: The French National Cancer Institute (INCa) support a 28 hospital platforms network for molecular testing of cancer patients. These platforms routinely assess a panel of biomarkers in order to speed up access of French cancer patients to targeted therapies (commercially available or through clinical trials). Regarding stage IV non-squamous NSCLC patients, 7 biomarkers are assessed including activating EGFR mutations, EML4-ALK translocation and EGFR T790M, KRAS, BRAF, HER2 and PI3KCA mutations. In 2012, up to 17 to 20,000 patients will be tested on this platform network. The objective of the BIOMARKERS-France study is to describe the epidemiological, clinical and molecular characteristics of these patients and their tumors and to assess the impact of these analyzes on their treatment (ie bio-guided therapy) as well as outcomes (response rate, progression free and overall survival). This study will collect, in a prospective way, data from a unique national cohort in order to guide future decisions regarding biomarker assessments (type? Number? Methods? Etc) in connexion with all the other research works currently ongoing in France.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Clinique Calabet - Centre de Radioth茅rapie et d'Oncologie, Agen, , France
Clinique Claude Bernard, Albi, , France
Clinique de l'Europe, Amiens, , France
CHU d'Angers, Angers, , France
H么pital Priv茅 d'Antony, Antony, , France
CHIC, Aulnay-Sous-Bois, , France
Auxerre - CH, Auxerre, , France
CH d'Avignon, Avignon, , France
CH de la C么te Basque, Bayonne, , France
CHU Besancon - Pneumologie, Besancon, , France
Blois - CH, Blois, , France
CHU Avicenne, Bobigny, , France
H么pital Ambroise Par茅 - Pneumologie, Boulogne, , France
H么pital Fleyriat, Bourg en Bresse, , France
H么pital de Brian莽on, Brian莽on, , France
CH de B茅ziers, B茅ziers, , France
CHU C么te de N芒cre, Caen, , France
Cahors - CH, Cahors, , France
CH de Cannes, Cannes, , France
Chambray Les Tours - Clinique L茅onard de Vinci, Chambray Les Tours, , France
CH de Chartres H么pital Louis Pasteur, Chartres, , France
Chevilly-Larue - CH, Chevilly-Larue, , France
H么pital de Cholet - Pneumologie, Cholet, , France
H么pital Percy-Arm茅es - Pneumologie, Clamart, , France
H么pital Pasteur, Colmar, , France
Clinique des C猫dres, Cornebarrieu, , France
Cr茅teil - CHI, Cr茅teil, , France
Dax - CH, Dax, , France
Denain - CH, Denain, , France
Dijon - CAC, Dijon, , France
Dijon - CHU, Dijon, , France
Draguignan - CH, Draguignan, , France
CH de Dreux, Dreux, , France
Elbeuf - CH, Elbeuf, , France
Epinal - CH, Epinal, , France
Ermont - Clinique Claude Bernard, Ermont, , France
Evreux - CH, Evreux, , France
Flers - CH, Flers, , France
CHICAS Site de Gap, Gap, , France
CHRU Grenoble, Grenoble, , France
Saint Omer - CHI, Helfaut, , France
Jonzac - CH, Jonzac, , France
La Roche Sur Yon - CH, La Roche Sur Yon, , France
Le Havre - HPE, Le Havre, , France
Le Mans - Centre Hospitalier, Le Mans, , France
Le Mans - Clinique Victor Hugo, Le Mans, , France
CH Dr Schaffner de Lens, Lens, , France
CHU (H么pital Calmette) - Pneumologie, Lille, , France
Lille - H么pital Calmette, Lille, , France
Limoges - H么pital du Cluzeau, Limoges, , France
Li茅vin - polyclinique de Riaumont, Li茅vin, , France
CH de Longjumeau, Longjumeau, , France
Lorient - CHBS, Lorient, , France
Clinique des 4 Pavillons, Lormont, , France
Lyon - Clinique Mutualiste, Lyon, , France
Clinique Mutualiste Eug猫ne Andr茅, Lyon, , France
HIA Desgenettes, Lyon, , France
H么pital de la Croix Rousse, Lyon, , France
Lyon - H么pital Louis Pradel (Pneumologie), Lyon, , France
Mantes La Jolie - CH, Mantes La Jolie, , France
Marseille - H么pital Sainte Marguerite, Marseille, , France
Marseille - CRLCC, Marseille, , France
Polyclinique du Parc, Maubeuge, , France
Meaux - CH, Meaux, , France
Metz - CHR, Metz, , France
Metz - Clinique Claude Bernard, Metz, , France
Metz - Belle Isle, Metz, , France
Mont de Marsan - CH, Mont de Marsan, , France
Montpellier - Clinique Cl茅mentville, Montpellier, , France
Montpellier - CHRU, Montpellier, , France
Moulins - CH, Moulins, , France
Mulhouse - CH, Mulhouse, , France
CHU Nancy, Nancy, , France
Nancy - Polyclinique Gentilly, Nancy, , France
Nanterre - CH, Nanterre, , France
Nantes - Centre Ren茅 Gauducheau, Nantes, , France
H么pital La毛nnec - CHU de Nantes, Nantes, , France
Narbonne - Polyclinique Le Languedoc, Narbonne, , France
Neuilly - H么pital Am茅ricain de Paris, Neuilly, , France
Nevers - CH, Nevers, , France
Nice - CAC, Nice, , France
N卯mes - Clinique Valdegour, N卯mes, , France
CHU, N卯mes, , France
Orl茅ans - CH, Orl茅ans, , France
Paris - Saint Louis, Paris, , France
Paris - h么pital Saint-Antoine, Paris, , France
GH Paris Saint-Joseph, Paris, , France
H么pital Bichat - Claude - Bernard, Paris, , France
H么pital du Val de Gr芒ce, Paris, , France
H么pital Europ茅en Georges Pompidou, Paris, , France
H么pital Tenon, Paris, , France
Paris - Curie, Paris, , France
Pau - CH, Pau, , France
Perpignan - Centre Catalan d'Oncologie, Perpignan, , France
Perpignan - Ch, Perpignan, , France
Lyon Sud, Pierre B茅nite, , France
CHU, Poitiers, , France
Pontoise - CH, Pontoise, , France
CH de P茅rigueux, P茅rigueux, , France
Reims - CHU, Reims, , France
Reims - CRLCC, Reims, , France
Rennes - CHU, Rennes, , France
CHG de Roanne, Roanne, , France
Rodez - CH, Rodez, , France
Roncq - Clinique Saint-Roch, Roncq, , France
Roubaix - CH, Roubaix, , France
Rouen - CHU, Rouen, , France
Centre Frederic Joliot, Rouen, , France
Saint Brieuc - CHG, Saint Brieuc, , France
Saint Nazaire - Centre Etienne Dolet, Saint Nazaire, , France
Saint Priest en Jarez - ICL, Saint Priest en Jarez, , France
Saint Quentin - CH, Saint Quentin, , France
Saint-Malo - CH, Saint-Malo, , France
Saint-Nazaire - CH, Saint-Nazaire, , France
Saverne - CH, Saverne, , France
Senlis - CH, Senlis, , France
Strasbourg - NHC, Strasbourg, , France
Suresnes - Hopital Foch, Suresnes, , France
Thonon les bains, Thonon les bains, , France
Toulon - CHI, Toulon, , France
Toulon - HIA, Toulon, , France
Clinique Saint Jean du Languedoc, Toulouse, , France
Toulouse - CHU Larrey, Toulouse, , France
Toulouse - Clinique Pasteur, Toulouse, , France
Tours - CHU, Tours, , France
Troyes - CH, Troyes, , France
Valenciennes - Clinique, Valenciennes, , France
Verdun - CHG, Verdun, , France
Vesoul - CHI, Vesoul, , France
CHI de la Haute-Sa么ne - Pneumologie, Vesoul, , France
Vienne - CH, Vienne, , France
Villejuif - Institut Gustave Roussy, Villejuif, , France
Clinique Mutualiste Les Portes du Sud, V茅nissieux, , France
Contact Details
Name: Fabrice Barlesi, PhD, MD
Affiliation: IFCT, Aix Marseille Universit茅 / Assistance Publique H么pitaux de Marseille
Role: PRINCIPAL_INVESTIGATOR
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