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Spots Global Cancer Trial Database for Panitumumab Plus Pemetrexed and Cisplatin (PemCisP) Versus PemCis in the First-line Treatment of Patients With Non-small Cell Lung Cancer

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Trial Identification

Brief Title: Panitumumab Plus Pemetrexed and Cisplatin (PemCisP) Versus PemCis in the First-line Treatment of Patients With Non-small Cell Lung Cancer

Official Title: CHAMP - An Open-label, Randomised, Multicentre, Phase II Clinical Study of Panitumumab Plus Pemetrexed and Cisplatin (PemCisP) Versus PemCis in the First-line Treatment of Patients With Stage IIIB or IV Primary Nonsquamous Non-small Cell Lung Cancer, With Particular Regard to the KRAS Status

Study ID: NCT01088620

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

Study Description

Brief Summary: The purpose of this trial is to estimate the therapeutic efficacy of the experimental targeted regimen including the EGFR antibody panitumumab (in combination with pemetrexed and cisplatin) in relation to the standard combination in patients with a KRAS wild-type stage IIIB or IV primary nonsquamous non-small cell lung cancer. It is expected that the progression free survival rate at 6 months is improved by the targeted regimen.

Detailed Description:

Keywords

Stage IIIb or IV

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Schwerpunktpraxis für Hämatologie und Internistische Onkologie, Gesundheitszentrum St. Marien GmbH, Amberg, , Germany

Universitätsklinikum Charité - Campus Mitte, Berlin, , Germany

Charité Campus Benjamin Franklin Medizinische Klinik m. S. Hämatologie und Onkologie, Berlin, , Germany

HELIOS Klinikum Emil von Behring - Lungenklinik Heckeshorn, Berlin, , Germany

Augusta-Kranken-Anstalt gGmbH, Bochum, , Germany

Johanniter-Krankenhaus Bonn, Bonn, , Germany

Carl-Thiem-Klinikum Cottbus gGmbH, Cottbus, , Germany

Medizinische Fakultät Carl Gustav Carus der Technischen Universität Dresden Medizinische Klinik 1, Dresden, , Germany

Katholisches Klinikum Duisburg/St. Johannes-Hospital, Duisburg, , Germany

Klinikum Frankfurt (Oder) GmbH, Frankfurt (Oder), , Germany

Krankenhaus Großhansdorf GmbH Onkologischer Schwerpunkt, Großhansdorf, , Germany

Krankenhaus - Martha-Maria Halle-Dölau GmbH, Halle/Saale, , Germany

Universitätsklinikum Halle (Saale), Klinik und Poliklinik für Innere Medizin I, Halle/Saale, , Germany

Universitätsklinikum Jena, Klinik für Innere Medizin I, Jena, , Germany

Onkologische Schwerpunktpraxis Dr. Stauch, Kronach, , Germany

Kliniken der Stadt Köln, Krankenhaus Merheim, Köln, , Germany

UK-SH, Campus Lübeck, Med. Klinik III, Lübeck, , Germany

LMU-Klinikum der Universität München, Medizinische Klinik München-Innenstadt, München, , Germany

Oncologianova GmbH, Recklinghausen, , Germany

Uniklinikum Ulm, Klinik für Innere Medizin II, Pneumologie, Ulm, , Germany

Contact Details

Name: Wolfgang Schütte, MD

Affiliation: Krankenhaus Martha-Maria Halle-Dölau

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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