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Brief Title: Gene Mutations in Non-Small Cell Lung Cancer Cells
Official Title: Detection of Gene Mutations in Non-small Cell Lung Cancer Cells in Blood Samples or Fine-needle Aspiration
Study ID: NCT00977509
Brief Summary: To compare the frequency of individual genetic abnormality between tumor cells and blood specimens.
Detailed Description: Samples will be collected before the systemic therapy. After initiation of therapy, samples will be collected at end of the 1st month, at the end of the 2nd month at the end of 3rd months and once every three months thereafter concurrently with the tumor assessment such as time of performing CT scans. In selected consented patients, peripheral blood samples will be collected every week for the first month. Disease status will be assessed every 2\~3 months and at the end of treatment according to RECIST criteria. If progression is not observed at the end of therapy, patients will be assessed every 3 months until progression or further anti-cancer therapy. Progression-free survival, overall survival and response rate will be reported.
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
National Taiwan University Hospital, Taipei, , Taiwan
Name: Chih-Hsin Yang, M.D., ph.D.
Affiliation: National Taiwan University College of Medicine
Role: PRINCIPAL_INVESTIGATOR