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Brief Title: BIBW 2992 (Afatinib) vs Gemcitabine-cisplatin in 1st Line Non-small Cell Lung Cancer (NSCLC)
Official Title: LUX-Lung 6: A Randomized, Open-label, Phase III Study of BIBW 2992 Versus Chemotherapy as First-line Treatment for Patients With Stage IIIB or IV Adenocarcinoma of the Lung Harbouring an EGFR Activating Mutation
Study ID: NCT01121393
Brief Summary: To investigate the efficacy and safety of BIBW 2992 compared to standard first-line chemotherapy in patients with stage IIIB or IV adenocarcinoma of the lung harbouring an EGFR activating mutation
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Beijing Chao-Yang Hospital, Beijing, , China
307 Hospital of PLA, Beijing, , China
Peking Union Medical College Hospital, Beijing, , China
Beijing Chest Hospital, Beijing, , China
First Hospital of Jilin University, Changchun, , China
Xiangya Hospital, Central South University, Changsha, , China
Hunan Province Tumor Hospital, Changsha, , China
West China Hospital, Chengdu, , China
Fujian Provincial Tumor Hospital, Fuzhou, , China
Guangdong General Hospital, Guangzhou, , China
Guangzhou Institute of Respiratory Disease, Guangzhou, , China
NanFang Hosptial, Guangzhou, , China
The Third Affiliated Hospital of Harbin Medical University, Haerbin, , China
Zhejiang Cancer Hospital, Hangzhou, , China
Hubei Cancer Hospital, HongShan, , China
Yunnan Provincial Tumor Hospital, Kunming, , China
Lin Yi Tumor Hospital, Linyi, , China
The Affiliated Cancer Hospital, Guangxi Medical University, Nan Ning, , China
the 81th Hospital of PLA, Nanjing, , China
Jiangsu Cancer Hospital, Nanjing, , China
The affiliated hospital of medicalcollege qingdao university, Qingdao, , China
Shanghai Changzheng Hospital, Shanghai, , China
Shanghai Chest Hospital, Shanghai, , China
Zhongshan Hospital Fudan University, Shanghai, , China
Shanghai Pulmonary Hospital, Shanghai, , China
Changhai Hospital, Shanghai, , China
The First Hospital of Chinese Medical University, Shenyang, , China
Hebei Provincial Tumor Hospital, Shijiazhuang, , China
Tangdu Hospital, Xi'An, , China
Northern Jiangsu People's Hospital, Yangzhou, , China
Kosin University Gospel Hospital, Busan, , Korea, Republic of
Chungbuk National University Hospital, Cheongju, , Korea, Republic of
Yeungnam University Medical Center, Daegu, , Korea, Republic of
Konkuk University Medical Center, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Songklanagarind Hospital, Songkla, , Thailand
Name: Boehringer Ingelheim
Affiliation: Boehringer Ingelheim
Role: STUDY_CHAIR