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Brief Title: Evaluation of BAY 59-8862 in Taxane Resistant Non-Small Cell Lung Cancer Patients
Official Title: An Uncontrolled, Phase II Study Evaluating Anti-Tumor Efficacy and Safety of BAY 59-8862 in Patients With Taxane Resistant Non-Small Cell Lung Carcinoma (NSCLC)
Study ID: NCT00044538
Brief Summary: Lung cancer is among the most common cancers in the world and its incidence continues to increase. Chemotherapy for patients with Non-Small Cell Lung Cancer (NSCLC) has been under investigation for several decades and several new drugs with activity in NSCLC have been identified. These include the taxanes, which are among the most commonly used class of chemotherapy agents in clinical oncology today. The usefulness of the taxanes is limited by the development of tumor resistance to these agents. This phase II trial with BAY 59-8862 will be conducted to determine the anti-tumor efficacy of BAY 59-8862 in taxane-resistant NSCLC.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Tucson, Arizona, United States
, Waterbury, Connecticut, United States
, Louisville, Kentucky, United States
, Metairie, Louisiana, United States
, Buffalo, New York, United States
, Columbus, Ohio, United States
, Nashville, Tennessee, United States
, Edmonton, Alberta, Canada
, Hamilton, Ontario, Canada
, Thunder Bay, Ontario, Canada
, Montreal, Quebec, Canada
, Quebec, , Canada
, Gauting, Bayern, Germany
, Berlin, , Germany
, Kfar Saba, , Israel
, Tel Aviv, , Israel
, Tel Hashomer, , Israel
, Modena, , Italy
, Parma, , Italy
, Pisa, , Italy
, Torino, , Italy
, Udine, , Italy
, Elche, Alicante, Spain
, Barakaldo, Bizkaia, Spain
, Barcelona, , Spain
, Madrid, , Spain
, Madrid, , Spain
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR