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Brief Title: Carboplatin, Paclitaxel and TLK286 (Telcyta) as First-Line Therapy in Advanced Non-Small Cell Lung Cancer
Official Title: Phase 1-2a Dose-Ranging Study of the Triplet Combination of Carboplatin, Paclitaxel and TLK286 as First-Line Therapy in Advanced Non-Small Cell Lung Cancer
Study ID: NCT00088556
Brief Summary: The purpose of this trial is to study the efficacy and safety of the triplet combination of TLK286, carboplatin and paclitaxel as first-line therapy for patients with advanced non-small cell lung cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Bay Area Cancer Research Group, Concord, California, United States
East Bay Medical Oncology/Hematology Associates, Concord, California, United States
Southwest Cancer Care, Escondido, California, United States
Kaiser Permanente Medical Center, Hayward, California, United States
Southwest Cancer Care, Murrieta, California, United States
Kaiser Permanente Medical Center, Oakland, California, United States
Southwest Cancer Care, Poway, California, United States
Kaiser Permanente Medical Center, Sacramento, California, United States
Kaiser Permanente Medical Center, San Francisco, California, United States
Kaiser Permanente Medical Center, San Jose, California, United States
Kaiser Permanente Medical Center, Santa Clara, California, United States
Kaiser Permanente Medical Center, So. San Francisco, California, United States
Kaiser Permanente Medical Center, Vallejo, California, United States
Diablo Valley Oncology & Hematology Medical Group, Walnut Creek, California, United States
Kaiser Permanente Medical Center, Walnut Creek, California, United States
Citrus Hematology and Oncology, Crystal River, Florida, United States
Citrus Hematology and Oncology Center, Inverness, Florida, United States
Florida Wellcare Alliance, LC, Inverness, Florida, United States
Kansas City Cancer Center, Kansas City, Kansas, United States
Kansas City Cancer Center - Central Research Dept. Data Office & Drug Discovery Location, Lenexa, Kansas, United States
Kansas City Cancer Center, Overland Park, Kansas, United States
Department of Veterns Affairs - Overton Brooks VA Medical Center, Shreveport, Louisiana, United States
LSU Health Sciences Center, Shreveport, Louisiana, United States
University of Maryland, Baltimore University of Maryland Medical System-Greenebaum Cancer Center, Baltimore, Maryland, United States
Center for Cancer and Blood Disorders, P. C., Bethesda, Maryland, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Brigham & Women's Hospital, Boston, Massachusetts, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Kansas City Cancer Center, Kansas City, Missouri, United States
Kansas City Cancer Center, Kansas City, Missouri, United States
Kansas City Cancer Center, Kansas City, Missouri, United States
Kansas City Cancer Center, Lee's Summit, Missouri, United States
St. John's Mercy Medical Center, St. Louis, Missouri, United States
St. John's Mercy Hospital, Washington, Missouri, United States
Clinical Research Service, Scottsbluff, Nebraska, United States
Horizons West Medical Group, Scottsbluff, Nebraska, United States
Dakota Cancer Institute, Fargo, North Dakota, United States
Odyssey Research, Fargo, North Dakota, United States
Tennessee Oncology, PLLC, Clarksville, Tennessee, United States
Tennessee Oncology, PLLC, Franklin, Tennessee, United States
Tennessee Oncology, PLLC, Hermitage, Tennessee, United States
Tennessee Oncology, PLLC, Lebanon, Tennessee, United States
Tennessee Oncology, PLLC, Murfreesboro, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Smyrna, Tennessee, United States
Texas Cancer Associates, Dallas, Texas, United States
Texas Cancer Associates, Plano, Texas, United States
Danville Hematology & Oncology, Inc., Danville, Virginia, United States