Spots Global Cancer Trial Database for Fluorine-18-α-Methyltyrosine Positron Emission Tomography for Diagnosis and Staging of Lung Cancer
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Trial Identification
Brief Title: Fluorine-18-α-Methyltyrosine Positron Emission Tomography for Diagnosis and Staging of Lung Cancer
Official Title:
Study ID: NCT00464282
Conditions
Interventions
Study Description
Brief Summary: Objective: L-\[3-18F\]-α-methyltyrosine (FMT) is an amino-acid tracer for PET. We evaluated the diagnostic usefulness of 18F-FMT PET in non-small cell lung cancer (NSCLC) patients. Tumor uptake of 18F-FMT PET was compared with 18F-FDG PET and the correlation with L-type amino acid transporter 1 (LAT1) expression also investigated. Method: Fifty patients with NSCLC were enrolled in this study, and a pair of PET study with 18F-FMT and 18F-FDG was performed. LAT1 expression and Ki-67 labeling index of the resected tumors were analyzed by immunohistochemical study.
Detailed Description:
Eligibility
Minimum Age: 8 Months
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
Locations
Contact Details
Name: kyoichi kaira, MD
Affiliation: Gunma Unversity Graduate School of Medicine
Role: PRINCIPAL_INVESTIGATOR
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