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Brief Title: GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma
Official Title: A Phase II Study of GW786034 Using a Randomised Discontinuation Design in Subjects With Locally Recurrent or Metastatic Clear-Cell Renal Cell Carcinoma
Study ID: NCT00244764
Brief Summary: Phase II, multi-center, two-stage study utilising a randomised discontinuation design to evaluate the safety and efficacy of GW786034 (pazopanib) in adult subjects with locally recurrent or metastatic clear-cell Renal Cell Carcinoma (RCC). After the interim analysis, the design was changed to an open label, single arm study with all subjects receiving pazopanib.
Detailed Description:
Minimum Age: 21 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
GSK Investigational Site, Duarte, California, United States
GSK Investigational Site, Los Angeles, California, United States
GSK Investigational Site, Orange, California, United States
GSK Investigational Site, San Francisco, California, United States
GSK Investigational Site, Aurora, Colorado, United States
GSK Investigational Site, Tucker, Georgia, United States
GSK Investigational Site, Indianapolis, Indiana, United States
GSK Investigational Site, New York, New York, United States
GSK Investigational Site, Cleveland, Ohio, United States
GSK Investigational Site, Cleveland, Ohio, United States
GSK Investigational Site, Nashville, Tennessee, United States
GSK Investigational Site, Dallas, Texas, United States
GSK Investigational Site, Camperdown, New South Wales, Australia
GSK Investigational Site, Kogarah, New South Wales, Australia
GSK Investigational Site, Randwick, New South Wales, Australia
GSK Investigational Site, East Melbourne, Victoria, Australia
GSK Investigational Site, Footscay, Victoria, Australia
GSK Investigational Site, Heidelberg, Victoria, Australia
GSK Investigational Site, Parkville, Victoria, Australia
GSK Investigational Site, Bruxelles, , Belgium
GSK Investigational Site, Bruxelles, , Belgium
GSK Investigational Site, Gent, , Belgium
GSK Investigational Site, Jette, , Belgium
GSK Investigational Site, Liège, , Belgium
GSK Investigational Site, Roeselare, , Belgium
GSK Investigational Site, Wilrijk, , Belgium
GSK Investigational Site, Guangzhou, Guangdong, China
GSK Investigational Site, Nanjing, Jiangsu, China
GSK Investigational Site, Jinan, Shandong, China
GSK Investigational Site, Hangzhou, Zhejiang, China
GSK Investigational Site, Beijing, , China
GSK Investigational Site, Beijing, , China
GSK Investigational Site, Shanghai, , China
GSK Investigational Site, Brno, , Czech Republic
GSK Investigational Site, Hradec Kralove, , Czech Republic
GSK Investigational Site, Praha 2, , Czech Republic
GSK Investigational Site, Hong Kong, , Hong Kong
GSK Investigational Site, Kowloon, , Hong Kong
GSK Investigational Site, Tuen Mun, , Hong Kong
GSK Investigational Site, Haifa, , Israel
GSK Investigational Site, Petach Tikva, , Israel
GSK Investigational Site, Tel Aviv, , Israel
GSK Investigational Site, Zrifin, , Israel
GSK Investigational Site, Taipei, , Taiwan
GSK Investigational Site, Taipei, , Taiwan
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR