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Brief Title: Study of Nexavar (Sorafenib, BAY 43-9006) in Patients With Advanced Refractory Cancer
Official Title: Randomized Discontinuation Study of BAY 43-9006 in Patients With Advanced Refractory Cancer.
Study ID: NCT00079612
Brief Summary: The purpose of the study is to: * Find out if BAY 43-9006 prevents the growth of tumors * For patients who have stable cancer status after 3 months of treatment if it is safer and/or more effective to continue to give BAY 43-9006 or to stop giving BAY 43-9006 at that time. * Find out how long the effect of BAY 43-9006 is on tumors. To assess the safety of BAY 43-9006 (sorafenib) in the treatment of advanced refractory cancers. * Measure the amount of BAY 43-9006 and some of its targets in the blood stream in some patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Chicago, Illinois, United States
, Philadelphia, Pennsylvania, United States
, Houston, Texas, United States
, San Antonio, Texas, United States
, London, Greater London, United Kingdom
, Glasgow, Strathclyde, United Kingdom
, Sutton, Surrey, United Kingdom
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR