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Brief Title: Evaluation of Bay 59-8862 in Patients With Advanced Renal Cell Carcinoma
Official Title: An Uncontrolled Phase II, Multi Center Trial Evaluating Antitumor Efficacy and Safety of Bay 59-8862 in Patients With Advanced Renal Cell Carcinoma
Study ID: NCT00044564
Brief Summary: In patients with renal cell cancer, most frequent methods of treatment include surgery, chemotherapy, hormonal therapy, and immunotherapy. Renal cell carcinoma is usually considered to be radioresistant and chemoresistant. In patients with metastatic disease, the options are limited. The taxanes are among the most commonly used class of chemotherapy agents in clinical oncology today but they are not effective in renal cancers; the development of Bay 59-8862 targets taxane-resistant tumors and the current protocol is designed to test the safety and efficacy of Bay 59-8862 in patients with advanced renal cell carcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, La Jolla, California, United States
, Muncie, Indiana, United States
, New Orleans, Louisiana, United States
, Baltimore, Maryland, United States
, Greenbelt, Maryland, United States
, Detroit, Michigan, United States
, Southfield, Michigan, United States
, St. Louis, Missouri, United States
, St. Louis, Missouri, United States
, Billings, Montana, United States
, New Brunswick, New Jersey, United States
, Salt Lake City, Utah, United States
, Milwaukee, Wisconsin, United States
, Calgary, Alberta, Canada
, Edmonton, Alberta, Canada
, Sudbury, Ontario, Canada
, Caen Cedex 5, , France
, Montpellier Cedex, , France
, Heidelberg, Baden-Württemberg, Germany
, Tübingen, Baden-Württemberg, Germany
, München, Bayern, Germany
, München, Bayern, Germany
, Düsseldorf, Nordrhein-Westfalen, Germany
, Münster, Nordrhein-Westfalen, Germany
, Rotterdam, , Netherlands
, Plymouth, Devon, United Kingdom
, Manchester, Greater Manchester, United Kingdom
, Cardiff, South Glamorgan, United Kingdom
, Sutton, Surrey, United Kingdom
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR