Spots Global Cancer Trial Database for Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.
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Trial Identification
Brief Title: Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.
Official Title: Mechanistic Evaluations on Sorafenib Induced Hypophosphatemia in Patients With Advanced Renal Cell Carcinoma
Study ID: NCT00622479
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to: 1. To elucidate the mechanism involved in the sorafenib-induced hypophosphatemia and possible early effect of hypophosphatemia on bone mineral density 2. A secondary objective to assess the effect sorafenib treatment on evaluate left ventricular function (LVEF) and Beta-type natriuretic peptide in plasma.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
, Scottsdale, Arizona, United States
, Jacksonville, Florida, United States
, Maywood, Illinois, United States
, Detroit, Michigan, United States
, Rochester, Minnesota, United States
, Hackensack, New Jersey, United States
, Stony Brook, New York, United States
Contact Details
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR
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