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Brief Title: An Observational Study to Evaluate the Efficacy and Safety of Avelumab + Axitinib Combination in Participants With aRCC (AVION)
Official Title: Real-world Evaluation of Efficacy and Safety With Avelumab (BAVENCIO®) + Axitinib (INLYTA®) in Patients With aRCC in Multiple EU Countries (AVION)
Study ID: NCT04941768
Brief Summary: The main purpose of this study is to expand knowledge on the effectiveness of Avelumab intravenous infusion in combination with Axitinib as the first-line therapy in participants with advanced renal-cell carcinoma (aRCC) in addition to the safety and tolerability under routine conditions of daily clinical practice.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Imelda Ziekenhuis, Bonheiden, , Belgium
AZ KLINA, Brasschaat, , Belgium
AZ Sint-Jan, Brugge, , Belgium
Klinikum St. Marien Amberg, Amberg, , Germany
Klinikum Aschaffenburg Medizinische Klinik, Aschaffenburg, , Germany
GFO Kliniken Rhein Berg, Bergisch Gladbach, , Germany
Zentrum für urologische Onkologie, Berlin, , Germany
Biberach, Biberach an der Riss, , Germany
Evangelisches Klinikum Bethel, Bielefeld, , Germany
Evangelisches Krankenhaus Bielefeld, Bielefeld, , Germany
Urologie im Schlosscarree, Braunschweig, , Germany
Donauisar Klinikum Deggendorf, Deggendorf, , Germany
Urologische Gemeinschaftspraxis, Dresden, , Germany
St. Georg Klinikum Eisenach gGmbH, Eisenach, , Germany
Universitatsklinikum Erlangen, Erlangen, , Germany
Universitaetsklinikum Essen Uroonkologie, Essen, , Germany
Universitätsklinik Frankfurt, Frankfurt, , Germany
Klinikum Friedrichshafen GmbH daVinci® -Zentrum Bodensee, Friedrichshafen, , Germany
Onkologische GP Dres. Wilke/Wagner/Petzoldt, Fürth, , Germany
Onkologische SP Praxis Fürth, Fürth, , Germany
MVZ Onkologische Kooperation Harz GbR, Goslar, , Germany
Praxis Dr. Maas, Halberstadt, , Germany
Universitätsklinikum Hamburg-Eppendorf, Hamburg, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
Vinzenzkrankenhaus Hannover, Hannover, , Germany
Praxis Kretz, Heinsberg, , Germany
Universitätskinderklinik Jena, Jena, , Germany
Städt. Klinikum Karlsruhe, Karlsruhe, , Germany
Urologische Praxis Dr. Ralf Eckert, L.-Eisleben, , Germany
Urologische Praxis Dipl. Med. Susanne Kloss, Luckenwalde, , Germany
Universitatsklinik Schleswig-Holstein, Lübeck, , Germany
Schwerpunktpraxis für Hämatologie und Onkologie, Magdeburg, , Germany
Johannes Wesling Klinikum Minden der Mühlenkreiskliniken (AöR), Minden, , Germany
Uniklinikum Münster, Münster, , Germany
University of Munster, Münster, , Germany
Paracelsus Klinik Osnabrück, Osnabrück, , Germany
medius Klinik Ostfildern-Ruit, Ostfildren, , Germany
Wissenschaftskontor Nord GmbH & Co. KG, Rostock, , Germany
GPR Klinikum Rüsselsheimg GmbH, Ruesselsheim, , Germany
SRH Kliniken Landkreis Sigmaringen (DEU), Sigmaringen, , Germany
Clinical Research Stolberg GmbH, Stolberg, , Germany
Hämatologie und Onkologie Stolberg, Stolberg, , Germany
Diakonie Krankenhaus Stuttgart, Stuttgart, , Germany
Praxis Troisdorf, Troisdorf, , Germany
Medizinische Studiengesellschaft Nord-West GmbH, Westerstede, , Germany
Lahn Dill Kliniken GmbH, Wetzlar, , Germany
Gen. Hos. "Alexandra", Athens, , Greece
General Hospital of Athens G.Gennimatas, Athens, , Greece
Henry Dunant Hospital Center, Athens, , Greece
University Hospital of Athens Sotiria, Athens, , Greece
Attikon Hospital, Attika, , Greece
Attikon, Chaidari, , Greece
General Hospital "Venizelio", Heraclion, , Greece
University Hospital of Ioannina, Ioannina, , Greece
Kavala General Hospital, Kavala, , Greece
University Hospital of Larissa, Larissa, , Greece
General Hospital of Patras "o Agios Andreas", Patras, , Greece
Metaxa Hospital, Piraeus, , Greece
Agios Loukas Hospital, Thessaloniki, , Greece
Bioclinic (GRC), Thessaloniki, , Greece
Papageorgiou Hospital, Thessaloniki, , Greece
Saint Luke Hospital, Thessaloniki, , Greece
Regional Oncology Dispensary - Irkutsk, Irkutsk, , Russian Federation
Name: Medical Responsible
Affiliation: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Role: STUDY_DIRECTOR