Spots Global Cancer Trial Database for Search for Predictors of Therapeutic Response in Ovarian Carcinoma

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Trial Identification

Brief Title: Search for Predictors of Therapeutic Response in Ovarian Carcinoma

Official Title: Search for Predictors of Therapeutic Response in Patients With Carcinoma of the Ovary, the Fallopian Tube or Peritoneal Serous-type Advanced

Study ID: NCT01391351

Conditions

Carcinoma of the Ovary

Fallopian Tube Cancer

Peritoneal Serous-type Advanced Stage

Interventions

blood samples

Study Description

Brief Summary: In order to search for predictors of response to chemotherapy in patients with ovarian carcinoma of the ovary, the fallopian tube or peritoneal serous-type advanced stage, we will define the comparative profiles of miRNA expression of serum polymorphisms and determine differential in 2 patient populations (with or without recurrence 6 months after completion of chemotherapy) with (i) the miRNA profile of serum before treatment and (ii) identification of polymorphisms or SNP (Single Nucleotide Polymorphism) in particular genes involved in the metabolism of chemotherapy agents In the case of miRNA, expression profiles will also be studied during the first course in response to chemotherapy. Indeed, the miRNA profile of serum may be different at baseline among the 2 types of populations (or non-recurrence at 6 months).

Detailed Description: