Spots Global Cancer Trial Database for Belinostat, Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Cancer of Unknown Primary
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Trial Identification
Brief Title: Belinostat, Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Cancer of Unknown Primary
Official Title: An Open-label Randomized Phase II Trial of Belinostat (PXD101) in Combination With Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Previously Untreated Carcinoma of Unknown Primary
Study ID: NCT00873119
Conditions
Study Description
Brief Summary: The purpose of this study is to assess efficacy and safety of belinostat in combination with carboplatin and paclitaxel in patients with previously untreated carcinoma of unknown primary.
Detailed Description: This is an open-label, multinational, multicenter, randomized, comparative efficacy and safety study in previously untreated patients with carcinoma of unknown primary. Patients meeting inclusion and exclusion criteria will be randomized to treatment in Arm A (BelCaP) or Arm B (CaP).
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Florida Cancer Specialists, Fort Myers, Florida, United States
Northwest Georgia Oncology Centers, Marietta, Georgia, United States
Baton Rouge Medical Center, Baton Rouge, Louisiana, United States
Center for Cancers and Blood Disorders, Bethesda, Maryland, United States
Research Medical Center, Kansas City, Missouri, United States
Oncology Hematology Care Inc., Cincinnati, Ohio, United States
South Carolina Oncology Associates, Columbia, South Carolina, United States
Chattanooga Oncology & Hematology Associates, PC, Chattanooga, Tennessee, United States
Tennessee Oncology Sarah Cannon Research, Nashville, Tennessee, United States
South Texas Oncology and Hematology, San Antonio, Texas, United States
Virginia Cancer Institute, Richmond, Virginia, United States
H:S Rigshospital, The Finsen Centre, Copenhagen, , Denmark
CRLCC Francois Baclesse, Oncologie medicale, Caen, , France
Centre Oscar Lambert, Lille, , France
Centre Léon Bérard, Oncologie, Lyon, , France
Centre Eugène Marquis, Rennes cedex, , France
Centre Henri Becquerel, Oncologie Médicale, Rouen, , France
Institut de Cancerologie de la Loire, Saint Priest en Jarez, , France
Institut Gustave Roussy IGR, Villejuif cedex, , France
Carl-Gustav-Carus Medicinische Klinik und Poliklinik I, Dresden, , Germany
Kliniken Essen-Mitte, Essen, , Germany
ASKLEPIOS Klinik Altona, Hamburg, , Germany
Ostholstein-Onkologie, Oldenburg in Holstein, , Germany
Contact Details
Name: e-mail contact via enquires@topotarget.com
Affiliation: Valerio Therapeutics
Role: STUDY_DIRECTOR
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