Spots Global Cancer Trial Database for Study of Weekly Paclitaxel and Cisplatin in FIGO IB2 and IIA2 Cervical Cancer Followed by Radical Hysterectomy
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Study of Weekly Paclitaxel and Cisplatin in FIGO IB2 and IIA2 Cervical Cancer Followed by Radical Hysterectomy
Official Title: Phase II Study of Weekly Paclitaxel and Cisplatin in FIGO IB2 and IIA2 Cervical Cancer Followed by Radical Hysterectomy
Study ID: NCT02432365
Conditions
Study Description
Brief Summary: The purpose was to establish a quick (7-day) cycle schedule of paclitaxel (60 mg/m2) combining with cisplatin (40 mg/m2) NAC regimen could be tolerated without interfering the following surgical treatment and a favorable overall survival rate for stages IB2 and IIA2 cervical squamous cell carcinoma (SCC).
Detailed Description: This is a multi-center, open-label, Simon's 2-stage, phase II study of paclitaxel and cisplatin as neoadjuvant therapy in patients with FIGO IB2 or IIA2, squamous cell cervical carcinoma of the uterine cervix. Primary Objectives: • Overall survival Secondary Objectives: * Safety * Progression-free survival * Response rate * Postoperative RT/CRT rate * To assess Quality-of-life An estimate of 64 evaluable patients will be enrolled in this phase II investigation.
Eligibility
Minimum Age: 35 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Chiayi City, , Taiwan
Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Kaohsiung, , Taiwan
Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, , Taiwan
Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Taipei, , Taiwan
Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital Linkou Medical Center, Taoyuan, , Taiwan
Contact Details
Name: Huei-Jean Huang, M.D
Affiliation: Gynecologic oncology
Role: PRINCIPAL_INVESTIGATOR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
