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Spots Global Cancer Trial Database for A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer

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Trial Identification

Brief Title: A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer

Official Title: A Phase II, Safety, and Efficacy Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Patients With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer

Study ID: NCT04300647

Conditions

Cervical Cancer

Study Description

Brief Summary: The purpose of this study is to evaluate the efficacy and safety of tiragolumab in combination with atezolizumab and atezolizumab monotherapy in patients with programmed death-ligand 1 (PD-L1)-positive cervical cancer (metastatic and/or recurrent).

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Arizona Oncology Associates, Phoenix, Arizona, United States

Kaiser Permanente - Irvine, Irvine, California, United States

Augusta University, Augusta, Georgia, United States

Oncology Associates of Oregon, P.C, Eugene, Oregon, United States

Mater Misericordiae Limited, South Brisbane, Queensland, Australia

Hospital Sao Rafael - HSR, Salvador, BA, Brazil

Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO, Brazil

Hospital de Caridade de Ijui; Oncologia, Ijui, RS, Brazil

Hospital Nossa Senhora da Conceicao, Porto Alegre, RS, Brazil

Hospital Sao Lucas - PUCRS, Porto Alegre, RS, Brazil

Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda, Sao Paulo, SP, Brazil

Royal Victoria Regional Health Centre, Barrie, Ontario, Canada

Hamilton Health Sciences - Juravinski Cancer Centre, Hamilton, Ontario, Canada

London Regional Cancer Centre, London, Ontario, Canada

Princess Margaret Cancer Center, Toronto, Ontario, Canada

Jewish General Hospital, Montreal, Quebec, Canada

McGill University Health Centre - Glen Site, Montreal, Quebec, Canada

Clinica CIMCA, San José, , Costa Rica

Oncotech S.A., San José, , Costa Rica

ICIMED Instituto de Investigación en Ciencias Médicas, San José, , Costa Rica

Centre Leon Berard, Lyon, , France

Institut Paoli Calmettes, Marseille, , France

Centre Régional de Lutte Contre Le Cancer Val D'aurelle Paul Lamarque, Montpellier, , France

ICO - Site René Gauducheau, Saint Herblain, , France

Gustave Roussy, Villejuif, , France

Istituto Tumori Napoli;Unità Operativa Oncologia Medica Uro-Ginecologica, Napoli, Campania, Italy

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna, Italy

Policlinico Universitario Agostino Gemelli, Roma, Lazio, Italy

IRCCS S. Raffaele; Ginecologia Oncologica, Milano, Lombardia, Italy

Istituto Europeo Di Oncologia, Milano, Lombardia, Italy

Keimyung University Dongsan Hospital, Daegu, , Korea, Republic of

Korea Cancer Center Hospital of Korea Institute of Radiological and Medical Sciences, Seoul, , Korea, Republic of

Seoul National University Hospital, Seoul, , Korea, Republic of

Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Gangnam Severance Hospital, Seoul, , Korea, Republic of

Samsung Medical Center, Seoul, , Korea, Republic of

Christus Muguerza Clinica Vidriera, Monterrey, Nuevo LEON, Mexico

Centro Oncológico de Panamá, Panama, , Panama

The Panama Clinic, Panama, , Panama

Clinica Ricardo Palma, San Isidro, , Peru

Bialostockie Centrum Onkologi, Bialystok, , Poland

Szpital Morski im.PCK; Oddzial Onkologii Klinicznej, Oddzial Dzienny, Gdynia, , Poland

Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; III Klin. Radioter. i Chemioter., Gliwice, , Poland

Wielkopolskie Centrum Onkologii im. M. Sklodowskiej-Curie, Poznan, , Poland

Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie;Klinika Ginekologii Onkologicznej, Warszawa, , Poland

FSBI "National Medical Research Center of Oncology N.N. Blokhin?, Moscow, Moskovskaja Oblast, Russian Federation

MEDSI Clinical Hospital on Pyatnitsky Highway; Department of antitumor drug therapy, Moscow, Moskovskaja Oblast, Russian Federation

Chelyabisnk regional clinical center for oncology and nuclear medicine, Chelyabinsk, Sverdlovsk, Russian Federation

Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic, Kazan, Tatarstan, Russian Federation

Murmansk Regional Clinical Hospital named after P.A. Bayandin, Murmansk, , Russian Federation

Tomsk scientific research institute of oncology SO RAMN, PAD; Pathological, Tomsk, , Russian Federation

Volgograd Regional Clinical Oncology Dispensary, Volgograd, , Russian Federation

Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, A Coruña, LA Coruña, Spain

Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, , Spain

Hospital Universitario La Paz; Servicio de Oncologia, Madrid, , Spain

Taichung Veterans General Hospital; Obstetrics and Gynecology, Taichung, , Taiwan

National Taiwan University Hospital; Obstetrics & Gynecology, Taipei City, , Taiwan

Taipei Veterans General Hospital, Taipei City, , Taiwan

Mackay Memorial Hospital; Obstetrics & Gynaecology, Taipei City, , Taiwan

Chang Gung Medical Foundation, Linkou Branch; Gynecologic Oncology, Taoyuan City, , Taiwan

Siriraj Hospital, Mahidol University, Bangkok, , Thailand

Maharaj Nakorn Chiang Mai Hospital; Faculty of Medicine Chiangmai University, Muang, , Thailand

University College London Hospital, London, , United Kingdom

Sarah Cannon Research Institute, London, , United Kingdom

Christie Hospital Nhs Trust; Medical Oncology, Manchester, , United Kingdom

Contact Details

Name: Clinical Trials

Affiliation: Hoffmann-La Roche

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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