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Brief Title: Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A Feasibility Study
Official Title: Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A Feasibility Study
Study ID: NCT04583254
Brief Summary: External radiation given in 25 fractions or so together with weekly chemotherapy and followed by 3 or 4 fractions of brachytherapy is the standard of care for patients with locally advanced cervical cancer. This study investigates the role of shortened external radiotherapy regimen (hypofractionated radiotherapy) by randomizing patients to this experimental regimen versus the standard of care.The purpose of this study is to access the feasibility of patient accrual to this trial in the Canadian setting and to provide an initial evaluation of cancer response and treatment tolerability.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
BC Cancer - Kelowna, Kelowna, British Columbia, Canada
London Health Sciences Centre - London Regional Cancer Program, London, Ontario, Canada
Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Name: Lucas C Mendez, MD
Affiliation: London Health Sciences Centre, Lawson Health Research Institute
Role: PRINCIPAL_INVESTIGATOR