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Spots Global Cancer Trial Database for A Phase II Study of Balstilimab Independently or in Combination With Zalifrelimab in Advanced Cervical Cancer

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Trial Identification

Brief Title: A Phase II Study of Balstilimab Independently or in Combination With Zalifrelimab in Advanced Cervical Cancer

Official Title: An Open-label, Multicenter Phase II Study Evaluating Balstilimab Alone or Balstilimab in Combination With Zalifrelimab in Patients With Advanced Cervical Cancer

Study ID: NCT05033132

Conditions

Cervical Cancer

Study Description

Brief Summary: This is an open-label, multi-center Phase II clinical trial to assess the efficacy, safety, and pharmacokinetics of Balstilimab (Treatment Arm 1 - monotherapy) or in combination with Zalifrelimab (Treatment Arm 2 - combination therapy) for treatment of patients with advanced cervical cancer who relapsed or progressed after receiving first-line platinum-based chemotherapy.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Betta Clinical Study Site 4, Bengbu, Anhui, China

Betta Clinical Study Site 2, Hefei, Anhui, China

Betta Clinical Study Site 3, Hefei, Anhui, China

Betta Clinical Study Site 27, Wuhu, Anhui, China

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Beijing, China

Betta Clinical Study Site 25, Beijing, Beijing, China

Betta Clinical Study Site 42, Chongqing, Chongqing, China

Betta Clinical Study Site 9, Fuzhou, Fujian, China

Betta Clinical Study Site 22, Xiamen, Fujian, China

Betta Clinical Study Site 41, Lanzhou, Gansu, China

Betta Clinical Study Site 39, Lanzhou, Gansu, China

Betta Clinical Study Site 14, Huizhou, Guangdong, China

Betta Clinical Study Site 18, Meizhou, Guangdong, China

Betta Clinical Study Site 10, Zhanjiang, Guangdong, China

Betta Clinical Study Site 11, Nanning, Guangxi, China

Betta Clinical Study Site 5, Cangzhou, Hebei, China

Betta Clinical Study Site 40, Harbin, Heilongjiang, China

Betta Clinical Study Site 43, Wuhan, Hubei, China

Betta Clinical Study Site 28, Wuhan, Hubei, China

Betta Clinical Study Site 12, Wuhan, Hubei, China

Betta Clinical Study Site 29, Wuhan, Hubei, China

Betta Clinical Study Site 31, Xiangyang, Hubei, China

Betta Clinical Study Site 6, Changde, Hunan, China

Betta Clinical Study Site 36, Changsha, Hunan, China

Betta Clinical Study Site 35, Changsha, Hunan, China

Betta Clinical Study Site 13, Changsha, Hunan, China

Betta Clinical Study Site 21, Nanjing, Jiangsu, China

Betta Clinical Study Site 8, Nanjing, Jiangsu, China

Betta Clinical Study Site 38, Ganzhou, Jiangxi, China

Betta Clinical Study Site 19, Nanchang, Jiangxi, China

Betta Clinical Study Site 20, Nanchang, Jiangxi, China

Betta Clinical Study Site 24, Shangrao, Jiangxi, China

Betta Clinical Study Site 16, Changchun, Jilin, China

Betta Clinical Study Site 15, Changchun, Jilin, China

Betta Clinical Study Site 7, Dalian, Liaoning, China

Betta Clinical Study Site 34, Shenyang, Liaoning, China

Betta Clinical Study Site 17, Shenyang, Liaoning, China

Betta Clinical Study Site 30, Xi'an, Shaanxi, China

Betta Clinical Study Site 23, Taiyuan, Shanxi, China

Betta Clinical Study Site 26, Tianjin, Tianjin, China

Betta Clinical Study Site 37, Tianjin, Tianjin, China

Betta Clinical Study Site 32, Ürümqi, Xinjiang, China

Betta Clinical Study Site 33, Hangzhou, Zhejiang, China

Contact Details

Name: Medical Director

Affiliation: Agenus Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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