Spots Global Cancer Trial Database for HPV-cytology Testing Versus Cytology Testing for the Detection of High Grade CIN
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Trial Identification
Brief Title: HPV-cytology Testing Versus Cytology Testing for the Detection of High Grade CIN
Official Title: A Randomized Controlled Trial Comparing Concomitant HPV-cytology Testing With Conventional Cytology Testing for the Detection of High Grade Cervical Intraepithelial Neoplasia in Primary Cervical Cancer Screening in Hong Kong
Study ID: NCT01058460
Interventions
Study Description
Brief Summary: To compare the effects of conventional cytology testing with concommitant HPV-cytology testing for the detection of high grade cervical lesions in primary cervical cancer screening in Hong Kong Hypotheses: 1. There is a significant difference in the number of CIN2+ cases detected between the cytology testing group and the cytology-HPV co-testing group at baseline. 2. Significantly more CIN2+ cases will be detected at the second round of screening among participants with normal cytology result in the control arm than those with normal cytology and negative HPV results in the intervention arm.
Detailed Description:
Eligibility
Minimum Age: 30 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
Department of Obstetrics & Gynaecology, The University of Hong Kong, Hong Kong SAR, , China
Contact Details
Name: Hextan YS Ngan, MD, MBBS
Affiliation: Department of Obstetrics & Gynaecology, The University of Hong Kong
Role: PRINCIPAL_INVESTIGATOR
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