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Brief Title: Clinical Study in Post-operation Treatment of Cervical Cancer
Official Title: Status and the Application of Topotecan at Post-operation Treatment of Cervical Cancer
Study ID: NCT01418859
Brief Summary: The purpose of the research is to evaluate the effect of additional chemotherapy in postoperation therapy of cervical cancer patients with risk factors (big tumor, deep invasion or tumor thrombi in the vascular system).
Detailed Description: Cervical cancer has a very high morbidity. Many patients need additional therapy after surgery in order to elevate the survival rate and life quality. In this research, we are going to give additional therapy to patients who have big tumor, deep invasion or tumor thrombi in the vascular system after surgery. randomized control method will be used in this research, in order to compare the survival rate and side effects between radiation therapy only, concurrent chemoradiotherapy, and concurrent chemoradiotherapy with additional chemotherapy. 3D-CRT and Topotecan will be used in this research.
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Xi'an Jiaotong University College of Medicine, Xi'an, Shanxi, China
Name: Chen M W, M.D
Affiliation: Affiliated Hospital of Medical College of Xo'an Jiaotong University
Role: STUDY_DIRECTOR