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Brief Title: Assessment of EGFR Genomic Alterations as Prognostic Markers in Cervical Cancer
Official Title: Assessment of EGFR Genomic Alterations as Prognostic Markers in Cervical Cancer
Study ID: NCT00298064
Brief Summary: The Tissue Repository will search for cases, pull slides, Paraffin-embedded tissue (PET) blocks.
Detailed Description: This study is done to gather preliminary data for determining the best way to test EGFR expression in patients with cervical cancer who will receive treatment with EGFR inhibitors in the future. This study is designed to obtain preliminary data of genomic and phenotypic alterations of the EGFR pathway in high grade cervical intraepithelial lesions (HG-SIL) and invasive cervical cancers (CC) to be used later for therapeutic guidance and to evaluate genomic (over-expression, amplification, point mutations, etc.) and phenotypic alterations of other transduction pathways interacting with the EGFR pathway.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
University of New Mexico, Albuquerque, New Mexico, United States
Name: Claire Verschraegen, MD
Affiliation: University of New Mexico
Role: PRINCIPAL_INVESTIGATOR