Spots Global Cancer Trial Database for Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer Trial

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Trial Identification

Brief Title: Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer Trial

Official Title: Feasibility, Safety, and Efficacy of Concomitant Curcumin in Patients Undergoing Palliative Radiotherapy for FIGO Stage IIIB-IVA Cervical Cancer: An Open-label Pilot Trial

Study ID: NCT05947513

Conditions

Cervical Cancer

Interventions

Curcumin

Palliative radiotherapy

Study Description

Brief Summary: The goal of this clinical trial is to test curcumin as an adjunct treatment in patients with cervical cancer receiving standard-of-care palliative radiation. The main questions it aims to answer are: * Is adding curcumin to standard-of-care palliative radiotherapy of cervical cancer patients safe? * Does adding curcumin to standard-of-care palliative radiotherapy of cervical cancer patients improve therapeutic responses? * How much curcumin is absorbed into the body and how long will it stay in the body? Participants will: * Take two 500 mg curcumin capsules twice per day for 4-6 weeks in addition to the prescribed palliative radiotherapy. * Provide blood and urine samples for laboratory tests. * Provide blood samples to measure curcumin levels in their body. * Obtain CT-scan to measure their tumor response. * Complete questioners to measure improvements to their quality of life, if any.

Detailed Description: