Spots Global Cancer Trial Database for Epigenetic and Metabolomic Changes in Childhood Cancer Survivors
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Trial Identification
Brief Title: Epigenetic and Metabolomic Changes in Childhood Cancer Survivors
Official Title: Epigenetic and Metabolomic Changes in Childhood Cancer Survivors as a Late Effect of Treatment - a Pilot Study
Study ID: NCT03866707
Conditions
Study Description
Brief Summary: The purpose of this research study is to try and identify markers in childhood cancer survivors to help predict if they will develop late effects from their cancer treatment.
Detailed Description: This is a pilot study to obtain preliminary data that will be used to apply for a larger grant to fund the full study with an adequate sample size for analysis. Specific Aim 1. What are the epigenetic differences between children treated for childhood cancers and healthy controls matched for age, sex, ethnicity, geographic region, and tanner stage. Specific Aim 2. Compare the metabolomic differences between children treated for childhood cancers and healthy controls matched for age, sex, ethnicity, geographic region, and tanner stage.
Keywords
Eligibility
Minimum Age: 1 Year
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Comprehensive Cancer Center of Wake Forest University, Winston-Salem, North Carolina, United States
Contact Details
Name: Kevin Buckley, MD
Affiliation: Wake Forest University Health Sciences
Role: PRINCIPAL_INVESTIGATOR
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