The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Brief Title: Photodynamic Therapy for Cholangiocarcinoma
Official Title: Evaluation of Bile Duct Patency After Photodynamic Therapy in Unresectable Cholangiocarcinoma:a Prospective Non-randomized Controlled Study
Study ID: NCT04860154
Brief Summary: Comparison of the bile duct patency with photodynamic therapy (PDT) and regular Endoscopic Retrograde Cholangiopancreatography(ERCP) stents in unresectable cholangiocarcinoma.
Detailed Description: Cholangiocarcinoma is a malignant tumor originating from the bile duct epithelium, accounting for about 70% of the malignant tumors of the bile duct system. Patients have no obvious clinical symptoms in the early stage. After late diagnosis, the effective treatment is surgical resection and \& or liver transplantation, and chemotherapy is only used as adjuvant or palliative treatment. Some types of cholangiocarcinomas, such as hilar cholangiocarcinomas, are difficult to achieve radical resection due to their anatomical location, early invasions and are prone to recurrence with a poor long-term efficacy after surgery. Therefore, the comprehensive treatment of cholangiocarcinoma by multiple means urgently needs to be explored. In recent years, photodynamic therapy (PDT), as a new local treatment method, has attracted increasing attention. This study investigates the bile duct patency and effectiveness of photodynamic therapy compare with ordinary ERCP treatment for cholangiocarcinoma including the median survival, overall survival, and other indicators of side effects.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Southwest Hospital, Army Medical University, Chongqing, Chongqing, China
The First Hospital of Lanzhou University, Lanzhou, Gansu, China
The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
The First Hospital of Jilin University, Changchun, Jilin, China
General Hospital of Ningxia Medical University, Yingchuan, Ningxia, China
The first affiliated hospital of Xi 'an JiaoTong university, Xi'an, Shaanxi, China
Shandong Provincial Third Hospital, Jinan, Shandong, China
Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
General Hospital of Taiyuan Iron and Steel Corporation, Taiyuan, Shanxi, China
The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang, China
Name: Xun Li, M.D.,Ph.D.
Affiliation: Hepatopancreatobiliary Surgery Institute of Gansu Province
Role: STUDY_CHAIR