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Spots Global Cancer Trial Database for Photodynamic Therapy for Cholangiocarcinoma

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Photodynamic Therapy for Cholangiocarcinoma

Official Title: Evaluation of Bile Duct Patency After Photodynamic Therapy in Unresectable Cholangiocarcinoma:a Prospective Non-randomized Controlled Study

Study ID: NCT04860154

Interventions

Hematoporphyrin

Study Description

Brief Summary: Comparison of the bile duct patency with photodynamic therapy (PDT) and regular Endoscopic Retrograde Cholangiopancreatography(ERCP) stents in unresectable cholangiocarcinoma.

Detailed Description: Cholangiocarcinoma is a malignant tumor originating from the bile duct epithelium, accounting for about 70% of the malignant tumors of the bile duct system. Patients have no obvious clinical symptoms in the early stage. After late diagnosis, the effective treatment is surgical resection and \& or liver transplantation, and chemotherapy is only used as adjuvant or palliative treatment. Some types of cholangiocarcinomas, such as hilar cholangiocarcinomas, are difficult to achieve radical resection due to their anatomical location, early invasions and are prone to recurrence with a poor long-term efficacy after surgery. Therefore, the comprehensive treatment of cholangiocarcinoma by multiple means urgently needs to be explored. In recent years, photodynamic therapy (PDT), as a new local treatment method, has attracted increasing attention. This study investigates the bile duct patency and effectiveness of photodynamic therapy compare with ordinary ERCP treatment for cholangiocarcinoma including the median survival, overall survival, and other indicators of side effects.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Southwest Hospital, Army Medical University, Chongqing, Chongqing, China

The First Hospital of Lanzhou University, Lanzhou, Gansu, China

The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

The First Hospital of Jilin University, Changchun, Jilin, China

General Hospital of Ningxia Medical University, Yingchuan, Ningxia, China

The first affiliated hospital of Xi 'an JiaoTong university, Xi'an, Shaanxi, China

Shandong Provincial Third Hospital, Jinan, Shandong, China

Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

General Hospital of Taiyuan Iron and Steel Corporation, Taiyuan, Shanxi, China

The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang, China

Contact Details

Name: Xun Li, M.D.,Ph.D.

Affiliation: Hepatopancreatobiliary Surgery Institute of Gansu Province

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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