Spots Global Cancer Trial Database for Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

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Trial Identification

Brief Title: Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

Official Title: Randomized Study of Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

Study ID: NCT00592748

Conditions

Chordoma

Chondrosarcoma

Interventions

Charged Particle Radiation Therapy

Study Description

Brief Summary: The primary purpose of this study is to determine if the administration of a higher dose would decrease the chance of tumor recurrence, compared to the risk of tumor recurrence with a lower dose. Most of the treatment will be given protons, but participants may receive a small portion of treatment with x-rays, because less radiation is given to the skin with x-rays. This study uses two slightly different doses of radiation It is not clear at this time which of the dose levels is better.

Detailed Description: * Participants will be assigned to a dose level by random chance, like flipping a coin. * A treatment plan will be determined by a treatment planning CT scan and will either involve 40-44 treatments or 37-40 treatments.