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Brief Title: Avastin for CNV Secondary to Pattern Dystrophy
Official Title: Intravitreal Avastin Injection for the Treatment of Choroidal Neovascularization Secondary to Pattern Dystrophy
Study ID: NCT00391144
Brief Summary: The natural history of subfoveal CNV secondary to Pattern Dystrophy is little understood, but it seems that visual function may be preserved only in the short-term follow-up, with progressive deterioration thereafter. Photodynamic therapy with verteporfin is the most studied therapeuthic option for this kindf of lesion, but unfortunately, this approach does not appear to guarantee long-term vision stabilization, and alternative therapies should be investigated.
Detailed Description: Diagnosis of Pattern Dystrophy Diagnosis of subfoveal CNV Intravitreal injection of avastin (1.25 mg) in operating room under sterile condition. Retreatment on the basis of the detection of disease progression and of lack of central retinal thickness reduction on OCT.
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste, Trieste, TS, Italy
Name: Maurizio B Parodi, MD
Affiliation: Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste
Role: PRINCIPAL_INVESTIGATOR
Name: Pierluigi Iacono, MD
Affiliation: Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste
Role: PRINCIPAL_INVESTIGATOR
Name: Giuseppe Ravalico, MD
Affiliation: Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste
Role: STUDY_DIRECTOR