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Brief Title: Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)
Official Title: Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)
Study ID: NCT00640523
Brief Summary: To evaluate the effectiveness and safety of forodesine in CLL patients
Detailed Description: To investigate the efficacy (complete response \[CR\] + partial response \[PR\]) of forodesine in treating subjects with CLL who have failed at least one prior treatment regimen or who are treatment naïve but are either elderly, have poor performance status or are otherwise predicted not to tolerate cytotoxic chemotherapy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Tower Cancer Research Foundation, Beverly Hills, California, United States
UCLA Medical Center, Los Angeles, California, United States
Indiana University Cancer Pavillion, Indianapolis, Indiana, United States
Center for Cancer & Blood Disorders, PC, Bethesda, Maryland, United States
Washington University School of Medicine, St. Louis, Missouri, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
Weill Cornell Medical College, New York, New York, United States
Oregon Health & Science University, Portland, Oregon, United States
Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia
Frankston Hospital, Frankston, Victoria, Australia
Cabrini Hospital, Malvern, Victoria, Australia
Name: Asher Chanan-Khan, MD
Affiliation: Roswell Park Cancer Institute
Role: PRINCIPAL_INVESTIGATOR