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Brief Title: Pneumococcal Vaccine in Untreated CLL Patients
Official Title: A Randomized Phase III Trial to Determine Whether Conjugated Pneumococcal Vaccine Can Improve the Immune Responsiveness Compared to Polyclonal Pneumococcal Vaccine in Patients With Untreated Chronic Lymphocytic Leukemia
Study ID: NCT01892618
Brief Summary: The purpose of the study is to determine whether patients with chronic lymphocytic leukaemia (CLL) will benefit from vaccination with a 13-valent conjugated pneumococcal vaccine, Prevenar13, compared with a conventional 23-valent capsular polysaccharide vaccine in terms of immune response.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Karolinska University Hospital, Stockholm, , Sweden
Name: Eva Kimby, Professor
Affiliation: Karolinska University Hospital, SE-141 86 Stockholm, Sweden
Role: PRINCIPAL_INVESTIGATOR