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Brief Title: Assess the Oral Bioavailability of New ABT-263 Formulations
Official Title: A Single Dose Study Evaluating the Oral Bioavailability and Pharmacokinetics of the Capsule Formulation of ABT-263 in Subjects With Cancer
Study ID: NCT00743028
Brief Summary: This is a randomized, open-label, multicenter crossover study to determine the oral bioavailability of new ABT-263 formulations relative to that of the current ABT-263 formulation being administered in ongoing Phase 1/2a studies. Approximately 36 evaluable subjects with lymphoid malignancies, including chronic lymphocytic leukemia, and solid tumors will be enrolled in this study.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Site Reference ID/Investigator# 10281, Encinitas, California, United States
Site Reference ID/Investigator# 10282, Santa Monica, California, United States
Site Reference ID/Investigator# 16341, Bethesda, Maryland, United States
Site Reference ID/Investigator# 9441, Lebanon, New Hampshire, United States
Site Reference ID/Investigator# 20041, Hackensack, New Jersey, United States