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Brief Title: Study of Motexafin Gadolinium (MGd) in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Official Title: Phase II Trial of Motexafin Gadolinium (MGd) in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma With Refractory or Relapsed Disease
Study ID: NCT00100711
Brief Summary: The primary purpose of this study is to determine if motexafin gadolinium may be an effective treatment for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Secondly, the duration of response and the time during which patients survive without chronic lymphocytic leukemia or small lymphocytic lymphoma worsening will be evaluated. Additionally, the patient's response to motexafin gadolinium will be compared to the response of the patient's cells in a laboratory to motexafin gadolinium.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Northwestern University, Chicago, Illinois, United States
The Mayo Clinic, Rochester, Minnesota, United States
The Ohio State University, Columbus, Ohio, United States
Name: Andrew Evens, D.O.
Affiliation: Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Role: PRINCIPAL_INVESTIGATOR
Name: Neil E. Kay, MD
Affiliation: Mayo Clinic
Role: PRINCIPAL_INVESTIGATOR