Spots Global Cancer Trial Database for Efficacy of Acalabrutinib in Very Old or Frail Patients With Treatment-naïve or Relapsed/Refractory CLL
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Trial Identification
Brief Title: Efficacy of Acalabrutinib in Very Old or Frail Patients With Treatment-naïve or Relapsed/Refractory CLL
Official Title: CLL-Frail - A Prospective, Multicenter Phase II Trial of Acalabrutinib in Very Old (≥80y) or Frail CLL-Patients
Study ID: NCT04883749
Conditions
Interventions
Study Description
Brief Summary: The aim of this trial is to show the efficacy, safety and feasibility of acalabrutinib in a cohort of CLL-patients ≥80 years or with a FRAIL scale score \>2 (5-item questionnaire to be filled out by the patient)
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Medizinische Universität Innsbruck, Innsbruck, , Austria
Hanusch Krankenhaus, Wien, , Austria
Onkologische Schwerpunktpraxis Kurfürstendamm, Berlin, , Germany
Donau-Isar-Klinikum Deggendorf Hämatologie/Onkologie, Deggendorf, , Germany
Oncoresearch Institut für klinische Studien GbR, Erlangen, , Germany
Universitaetsklinikum Essen, Essen, , Germany
Onkologische Kooperation Harz, Goslar, , Germany
OncoResearch Lerchenfeld, Hamburg, , Germany
MediProjekt GBR, Hannover, , Germany
Universitaetsklinikum Schleswig-Holstein Campus Kiel, Kiel, , Germany
Praxis fuer Haematologie und Onkologie, Koblenz, , Germany
Universitätsklinik Köln, Köln, , Germany
H.O.T Praxis Landshut, Landshut, , Germany
Lübecker Onkologische Schwerpunktpraxis, Lübeck, , Germany
Gemeinschaftspraxis Haematologie und Onkologie, Magdeburg, , Germany
Gemeinschaftspraxis für Hämatologie und Onkologie, Muenster, , Germany
Brüderkrankenhaus St. Josef Paderborn, Paderborn, , Germany
Gemeinschaftspraxis für Hämatologie und Onkologie, Ravensburg, , Germany
Universitaetsklinikum Ulm, Ulm, , Germany
Hämatologisch Onkologische Schwerpunktpraxis, Würzburg, , Germany
Contact Details
Name: Barbara Eichhorst, Prof.
Affiliation: Department I of Internal Medicine, University Hospital Cologne
Role: PRINCIPAL_INVESTIGATOR
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