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Brief Title: CML Treated With Bosutinib After Relapse
Official Title: Single Nucleotide Polymorphism Association With Response and Toxic Effects in Patients With Ph+ CP-CML Treated With Bosutinib After Relapse to Previous Treatment
Study ID: NCT02445742
Brief Summary: Prospective, open label, multicenter, phase II study evaluating correlation of SNPs with efficacy and toxicity in patients treated with Bosutinib. A total of 50 patients with previously treated Ph+ chronic phase CML will be included in the study
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
C. H. U. de Gran Canaria Dr. Negrín, Gran Canaria, , Spain
C. H. Gregorio Marañón, Madrid, , Spain
C. U. La Paz - H. U. La Paz, Madrid, , Spain
H. Ramón y Cajal, Madrid, , Spain
H. U. de la Princesa, Madrid, , Spain
H. U. Fundación Jiménez Díaz, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
C. H. Regional de Málaga , H. General, Málaga, , Spain
H. U. Son Espases, Palma de Mallorca, , Spain
C. Asistencial U. de Salamanca, Salamanca, , Spain
C. H. U. de Santiago, Santiago de Compostela, , Spain
H. Virgen de la Salud, Toledo, , Spain
Clínica Quirón Zaragoza S.A., Zaragoza, , Spain
Name: Luis Felipe Casado, Dr
Affiliation: PETHEMA Foundation
Role: STUDY_CHAIR