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Spots Global Cancer Trial Database for Safety and Efficacy of Imatinib Versus Interferon-α Plus Cytarabine in Patients With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia

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Trial Identification

Brief Title: Safety and Efficacy of Imatinib Versus Interferon-α Plus Cytarabine in Patients With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia

Official Title: A Phase III Study of STI571 Versus Interferon-α (IFN-α) Combined With Cytarabine (Ara-C) in Patients With Newly Diagnosed Previously Untreated Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)

Study ID: NCT00333840

Conditions

Chronic Myelogenous Leukemia

Interventions

imatinib mesilate

interferon-alpha (INF-a)

cytarabine (ARA-C)

Study Description

Brief Summary: The purpose of this study is to evaluate and compare the side effects and anti-leukemic benefits of imatinib with those of interferon and Ara-C for patients who have chronic myeloid leukemia (CML) in the chronic phase. Patients in this study will be randomized (1:1) to receive either interferon plus Ara-C or imatinib as initial treatment.

Detailed Description:

Keywords

chronic myeloid leukemia

Philadelphia chromosome positive

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Novartis Investigative Site, Birmingham, Alabama, United States

Novartis Investigative Site, Montgomery, Alabama, United States

Novartis Investigative Site, Tucson, Arizona, United States

Novartis Investigative Site, Berkeley, California, United States

Novartis Investigative Site, Campbell, California, United States

Novartis Investigative Site, Duarte, California, United States

Novartis Investigative Site, La Jolla, California, United States

Novartis Investigative Site, Denver, Colorado, United States

Novartis Investigative Site, Miami, Florida, United States

Novartis Investigative Site, Orlando, Florida, United States

Novartis Investigative Site, Atlanta, Georgia, United States

Novartis Investigative Site, Honolulu, Hawaii, United States

Novartis Investigative Site, Chicago, Illinois, United States

Novartis Investigative Site, Decatur, Illinois, United States

Novartis Investigative Site, Beech Grove, Indiana, United States

Novartis Investigative Site, Witchita, Kansas, United States

Novartis Investigative Site, Louisville, Kentucky, United States

Novartis Investigative Site, New Orleans, Louisiana, United States

Novartis Investigative Site, Baltimore, Maryland, United States

Novartis Investigative Site, Boston, Massachusetts, United States

Novartis Investigative Site, Worcester, Massachusetts, United States

Novartis Investigative Site, Ann Arbor, Michigan, United States

Novartis Investigative Site, Detroit, Michigan, United States

Novartis Investigative Site, East Lansing, Michigan, United States

Novartis Investigative Site, Minneapolis, Minnesota, United States

Novartis Investigative Site, St. Louis, Missouri, United States

Novartis Investigative Site, Billings, Montana, United States

Novartis Investigative Site, Omaha, Nebraska, United States

Novartis Investigative Site, Hackensack, New Jersey, United States

Novartis Investigative Site, Alburquerque, New Mexico, United States

Novartis Investigative Site, Farmington, New Mexico, United States

Novartis Investigative Site, Buffalo, New York, United States

Novartis Investigative Site, New York, New York, United States

Novartis Investigative Site, Syracuse, New York, United States

Novartis Investigative Site, Chapel Hill, North Carolina, United States

Novartis Investigative Site, Charlotte, North Carolina, United States

Novartis Investigative Site, Durham, North Carolina, United States

Novartis Investigative Site, Winston-Salem, North Carolina, United States

Novartis Investigative Site, Cleveland, Ohio, United States

Novartis Investigative Site, Columbus, Ohio, United States

Novartis Investigative Site, Dayton, Ohio, United States

Novartis Investigative Site, Tulsa, Oklahoma, United States

Novartis Investigative Site, Portland, Oregon, United States

Novartis Investigative Site, Pittsburg, Pennsylvania, United States

Novartis Investigative Site, Providence, Rhode Island, United States

Novartis Investigative Site, Spartanburg, South Carolina, United States

Novartis Investigative Site, Memphis, Tennessee, United States

Novartis Investigative Site, Nashville, Tennessee, United States

Novartis Investigative Site, Dallas, Texas, United States

Novartis Investigative Site, Houston, Texas, United States

Novartis Investigative Site, Salt Lake City, Utah, United States

Novartis Investigative Site, Seattle, Washington, United States

Novartis Investigative Site, Milwaukee, Wisconsin, United States

Novartis Investigative Site, Adelaide, , Australia

Novartis Investigative Site, Brisbane, , Australia

Novartis Investigative Site, Darlinghurst, , Australia

Novartis Investigative Site, East Melbourne, , Australia

Novartis Investigative Site, Nedlands, , Australia

Novartis Investigative Site, Parkville, , Australia

Novartis Investigative Site, Prahan, , Australia

Novartis Investigative Site, South Brisbane, , Australia

Novartis Investigative Site, St. Leonards, , Australia

Novartis Investigative Site, Sydney, , Australia

Novartis Investigative Site, Westmead, , Australia

Novartis Investigative Site, Wien, , Austria

Novartis Investigative Site, Bruxelles, , Belgium

Novartis Investigative Site, Godinne, , Belgium

Novartis Investigative Site, Leuven, , Belgium

Novartis Investigative Site, Calgary, Alberta, Canada

Novartis Investigative Site, Edmonton, Alberta, Canada

Novartis Investigative Site, Vancouver, British Columbia, Canada

Novartis Investigative Site, Winnipeg, Manitoba, Canada

Novartis Investigative Site, Halifax, Nova Scotia, Canada

Novartis Investigative Site, Hamilton, Ontario, Canada

Novartis Investigative Site, London, Ontario, Canada

Novartis Investigative Site, Ottawa, Ontario, Canada

Novartis Investigative Site, Toronto, Ontario, Canada

Novartis Investigative Site, Montreal, Quebec, Canada

Novartis Investigative Site, Arhus, , Denmark

Novartis Investigative Site, Copenhagen, , Denmark

Novartis Investigative Site, Herlev, , Denmark

Novartis Investigative Site, Creteil, , France

Novartis Investigative Site, Lille, , France

Novartis Investigative Site, Lyon, , France

Novartis Investigative Site, Marseille, , France

Novartis Investigative Site, Nantes, , France

Novartis Investigative Site, Paris, , France

Novartis Investigative Site, Pessac, , France

Novartis Investigative Site, Poitiers, , France

Novartis Investigative Site, Strasbourg, , France

Novartis Investigative Site, Vandoeuvre-les-Nancy, , France

Novartis Investigative Site, Berlin, , Germany

Novartis Investigative Site, Dresden, , Germany

Novartis Investigative Site, Dusseldorf, , Germany

Novartis Investigative Site, Frankfurt, , Germany

Novartis Investigative Site, Freiburg, , Germany

Novartis Investigative Site, Hamburg, , Germany

Novartis Investigative Site, Heidelberg, , Germany

Novartis Investigative Site, Leipzig, , Germany

Novartis Investigative Site, Mainz, , Germany

Novartis Investigative Site, Mannheim, , Germany

Novartis Investigative Site, Marburg, , Germany

Novartis Investigative Site, Muenchen, , Germany

Novartis Investigative Site, Munchen, , Germany

Novartis Investigative Site, Regensburg, , Germany

Novartis Investigative Site, Rostock, , Germany

Novartis Investigative Site, Stuttgart, , Germany

Novartis Investigative Site, Bari, , Italy

Novartis Investigative Site, Bologna, , Italy

Novartis Investigative Site, Firenze, , Italy

Novartis Investigative Site, Genova, , Italy

Novartis Investigative Site, Milano, , Italy

Novartis Investigative Site, Napoli, , Italy

Novartis Investigative Site, Orbassano, , Italy

Novartis Investigative Site, Pavia, , Italy

Novartis Investigative Site, Pescara, , Italy

Novartis Investigative Site, Pisa, , Italy

Novartis Investigative Site, Reggio Calabria, , Italy

Novartis Investigative Site, Amsterdam, , Netherlands

Novartis Investigative Site, Rotterdam, , Netherlands

Novartis Investigative Site, Auckland, , New Zealand

Novartis Investigative Site, Oslo, , Norway

Novartis Investigative Site, Tromso, , Norway

Novartis Investigative Site, Barcelona, , Spain

Novartis Investigative Site, Madrid, , Spain

Novartis Investigative Site, Salamanca, , Spain

Novartis Investigative Site, Valencia, , Spain

Novartis Investigative Site, Goteborg, , Sweden

Novartis Investigative Site, Linkoping, , Sweden

Novartis Investigative Site, Lund, , Sweden

Novartis Investigative Site, Orebro, , Sweden

Novartis Investigative Site, Stockholm, , Sweden

Novartis Investigative Site, Umea, , Sweden

Novartis Investigative Site, Uppsala, , Sweden

Novartis Investigative Site, Basel, , Switzerland

Novartis Investigative Site, Bern, , Switzerland

Novartis Investigative Site, St. Gallen, , Switzerland

Novartis Investigative Site, Birmingham, , United Kingdom

Novartis Investigative Site, Cambridge, , United Kingdom

Novartis Investigative Site, Cardiff, , United Kingdom

Novartis Investigative Site, Leeds, , United Kingdom

Novartis Investigative Site, Liverpool, , United Kingdom

Novartis Investigative Site, London, , United Kingdom

Novartis Investigative Site, Manchester, , United Kingdom

Novartis Investigative Site, Nottingham, , United Kingdom

Novartis Investigative Site, Plymouth, , United Kingdom

Contact Details

Name: Novartis Pharmaceuticals

Affiliation: Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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