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Brief Title: Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological Malignancies
Official Title: A Phase 1 Dose Escalation Trial to Determine the Safety, Tolerability and Maximum Tolerated Dose of Oral AP24534 in Patients With Refractory or Advanced Chronic Myelogenous Leukemia and Other Hematologic Malignancies
Study ID: NCT00660920
Brief Summary: The purpose of this study is to determine the maximum tolerated dose or a recommended dose of oral AP24534 in a defined schedule in patients with refractory or advanced chronic myelogenous leukemia and other refractory hematologic malignancies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
ARIAD Investigational Site #075, San Francisco, California, United States
ARIAD Investigational Site #011, Ann Arbor, Michigan, United States
ARIAD Investigational Site #048, Portland, Oregon, United States
ARIAD Investigational Site #076, Nashville, Tennessee, United States
ARIAD Investigational Site #005, Houston, Texas, United States