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Brief Title: European CML Blast Crisis Register
Official Title: European CML Blast Crisis Register
Study ID: NCT03869502
Brief Summary: Multicentric prospective and retrospective register collecting patient with CML blast crisis diagnosed in Germany and Europe
Detailed Description: Since the advent of treatment with tyrosine kinase inhibitors (TKI), the incidence of blast crises has significantly decreased. Nevertheless, about 5% of patients diagnosed with chronic myeloid leukemia (CML) will evolve into a blast phase at some point during the course of their disease. Furthermore, despite the advances made in CML treatment, outcome of patients with blast crises are still dismal. Due to the rarity of this condition clinical trials are challenging, and collaboration between researchers both at national and international level is needed to collect a meaningful number of data.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Masaryk University Hospital Brno, Brno, , Czechia
Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden, , Germany
Universitätsklinikum Essen, Essen, , Germany
University Hospital Jena, Jena, , Germany
Universitätsklinikum Leipzig AöR, Leipzig, , Germany
Universitätsmedizin Mannheim, Mannheim, , Germany
Universitaetsklinikum Muenster, Münster, , Germany
I. P. Pavlov First St. Petersburg State Medical University, Saint Petersburg, , Russian Federation
National Research Center for Radiation Medicine, Kiev, , Ukraine
Name: Annamaria Brioli, PhD MD
Affiliation: Univerity of Jena
Role: PRINCIPAL_INVESTIGATOR