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Brief Title: Allogeneic Tumor Cell Vaccination in Patients With Chronic Myeloid Leukemia
Official Title: Allogeneic Tumor Cell Vaccination in Patients With Chronic Myeloid Leukemia
Study ID: NCT00162513
Brief Summary: Donors with CM will be solicited from a waiting list of patients awaiting BMT from the waiting list of MUD searches. Maximally matched donor will be searched for each eligible CML patient with a goal in mind to find other patients with CML that share both class I and class II determinants. Sharing of one class I II will be considered eligible for participation in the study. Peripheral blood and PBMC from the donors will be isolated, washed and irradiated. The cells will be injected into the consenting patients intracutaneously at 2 weeks intervals for a total of 6 injections.
Detailed Description:
Minimum Age: 55 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hadassah Medical Organization, Jerusalem, , Israel
Name: Shimon Slavin, MD
Affiliation: Hadassah Medical Organization
Role: PRINCIPAL_INVESTIGATOR