Spots Global Cancer Trial Database for Dasatinib (BMS-354835) Versus Imatinib Mesylate in Subjects With Chronic Myeloid Leukemia
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Trial Identification
Brief Title: Dasatinib (BMS-354835) Versus Imatinib Mesylate in Subjects With Chronic Myeloid Leukemia
Official Title: A Randomized Multi-Center Open Label Study of BMS-354825 vs. Imatinib Mesylate (Gleevec) 800 mg/d in Subjects With Chronic Phase Philadelphia Chromosome-Positive Chronic Myeloid Leukemia Who Have Disease That is Resistant to Imatinib at a Dose at 400 - 600 mg/d
Study ID: NCT00103844
Study Description
Brief Summary: The primary purpose of this study is to estimate the major cytogenetic response rates of BMS-354825 and imatinib (800 mg/d) in subjects with chronic phase, Philadelphia chromosome positive, chronic myeloid leukemia (PH+ CML) with disease resistant to imatinib at a dose of 400-600 mg/d.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Local Institution, Birmingham, Alabama, United States
Local Institution, Anaheim, California, United States
Local Institution, Bakersfield, California, United States
Local Institution, Fullerton, California, United States
Local Institution, Loma Linda, California, United States
Local Institution, Los Angeles, California, United States
Local Institution, Monterey Park, California, United States
Local Institution, San Diego, California, United States
Local Institution, Santa Barbara, California, United States
Local Institution, Santa Maria, California, United States
Local Institution, Stanford, California, United States
Local Institution, Vallejo, California, United States
Local Institution, Aurora, Colorado, United States
Local Institution, Hartford, Connecticut, United States
Local Institution, Washington, District of Columbia, United States
Local Institution, Jacksonville, Florida, United States
Local Institution, Tampa, Florida, United States
Local Institution, Athens, Georgia, United States
Local Institution, Atlanta, Georgia, United States
Local Institution, Lawrenceville, Georgia, United States
Local Institution, Tucker, Georgia, United States
Local Institution, Chicago, Illinois, United States
Local Institution, Peoria, Illinois, United States
Local Institution, Indianapolis, Indiana, United States
Local Institution, Kansas City, Kansas, United States
Local Institution, Lexington, Kentucky, United States
Local Institution, Boston, Massachusetts, United States
Local Institution, Minneapolis, Minnesota, United States
Local Institution, Rochester, Minnesota, United States
Local Institution, Columbia, Missouri, United States
Local Institution, Kansas City, Missouri, United States
Local Institution, St. Louis, Missouri, United States
Local Institution, Omaha, Nebraska, United States
Local Institution, Hackensack, New Jersey, United States
Local Institution, Morristown, New Jersey, United States
Local Institution, New Brunswick, New Jersey, United States
Local Institution, Cary, North Carolina, United States
Local Institution, Chapel Hill, North Carolina, United States
Local Institution, Oklahoma City, Oklahoma, United States
Local Institution, Tulsa, Oklahoma, United States
Local Institution, Portland, Oregon, United States
Local Institution, Pittsburgh, Pennsylvania, United States
Local Institution, Greenville, South Carolina, United States
Local Institution, Nashville, Tennessee, United States
Local Institution, Dallas, Texas, United States
Local Institution, Fort Worth, Texas, United States
Local Institution, Houston, Texas, United States
Local Institution, San Antonio, Texas, United States
Local Institution, Tyler, Texas, United States
Local Institution, Norfolk, Virginia, United States
Local Institution, Seattle, Washington, United States
Local Institution, Spokane, Washington, United States
Local Institution, Vancouver, Washington, United States
Local Institution, Buenos Aires, , Argentina
Local Institution, Cordoba, , Argentina
Local Institution, Camperdown, New South Wales, Australia
Local Institution, St. Leonards, New South Wales, Australia
Local Institution, South Brisbane, Queensland, Australia
Local Institution, Adelaide, South Australia, Australia
Local Institution, Perth, Western Australia, Australia
Local Institution, Wein, , Austria
Local Institution, B-Leuven, , Belgium
Local Institution, Brugge, , Belgium
Local Institution, Bruxelles, , Belgium
Local Institution, Charleroi, , Belgium
Local Institution, Edegem, , Belgium
Local Institution, Yvoir, , Belgium
Local Institution, Curitiba, Parana, Brazil
Local Institution, Rio De Janeiro, , Brazil
Local Institution, Sao Paulo, , Brazil
Local Institution, Edmonton, Alberta, Canada
Local Institution, Vancouver, British Columbia, Canada
Local Institution, Toronto, Ontario, Canada
Local Institution, Montreal, Quebec, Canada
Local Institution, Beijing, , China
Local Institution, Shanghai, , China
Local Institution, Aarhus, , Denmark
Local Institution, Tallin, , Estonia
Local Institution, Helsinki, , Finland
Local Institution, Lille, , France
Local Institution, Lyon Cedex 03, , France
Local Institution, Nantes, , France
Local Institution, Paris, , France
Local Institution, Pessac, , France
Local Institution, Poitiers, , France
Local Institution, Strasbourg Cedex, , France
Local Institution, Dresden, , Germany
Local Institution, Groenkloof, , Germany
Local Institution, Hamburg, , Germany
Local Institution, Leipzig, , Germany
Local Institution, Mainz, , Germany
Local Institution, Mannheim, , Germany
Local Institution, Budapest, , Hungary
Local Institution, Dublin, , Ireland
Local Institution, Ramat-Gan, , Israel
Local Institution, Bari, , Italy
Local Institution, Bologna, , Italy
Local Institution, Milano, , Italy
Local Institution, Napoli, , Italy
Local Institution, Orbassano, , Italy
Local Institution, Roma, , Italy
Local Institution, Kyunggi-Do, , Korea, Republic of
Local Institution, Trondheim, , Norway
Local Institution, Lima, , Peru
Local Institution, Quezon City, , Philippines
Local Institution, Katowice, , Poland
Local Institution, Krakow, , Poland
Local Institution, Lublin, , Poland
Local Institution, Warsaw, , Poland
Local Institution, San Juan, , Puerto Rico
Local Institution, Moscow, , Russian Federation
Local Institution, St. Petersburg, , Russian Federation
Local Institution, Singapore, , Singapore
Local Institution, Bloemfontein, Free State, South Africa
Local Institution, Parktown, Gauteng, South Africa
Local Institution, Soweto, Gauteng, South Africa
Local Institution, Barcelona, , Spain
Local Institution, Madrid, , Spain
Local Institution, Gothenburg, , Sweden
Local Institution, Lund, , Sweden
Local Institution, Stockholm, , Sweden
Local Institution, Umea, , Sweden
Local Institution, Uppsala, , Sweden
Local Institution, Basel, , Switzerland
Local Institution, Bellinzona, , Switzerland
Local Institution, Taipei, , Taiwan
Local Institution, Taoyuan, , Taiwan
Local Institution, Bangkok, , Thailand
Local Institution, Glasglow, Central, United Kingdom
Local Institution, London, Greater London, United Kingdom
Local Institution, Newcastle, Tyne and Wear, United Kingdom
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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