Spots Global Cancer Trial Database for CALLS: CML and Ph+ALL Low Level Mutation Prevalence Survey
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Trial Identification
Brief Title: CALLS: CML and Ph+ALL Low Level Mutation Prevalence Survey
Official Title: A Cohort Study To Establish the Prevalence of Mutations in Patients With CML Who Meet the ELN Criteria for Warning or Failure and Patients With Ph+ ALL With Detectable BCR-ABL Currently Being Treated With First or Subsequent TKI Therapy in the UK, Ireland, or France Using Next-Generation Sequencing
Study ID: NCT03647215
Interventions
Study Description
Brief Summary: A multicenter, prospective cohort study of the mutation status of patients with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who are being treated with first or subsequent tyrosine kinase inhibitor (TKI) therapy in the UK, Ireland, or France.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Limerick University Hospital, Limerick, Dooradoyle, Ireland
University Hospital Waterford, Waterford, , Ireland
Royal Cornwall Hospital, Truro, Cornwall, United Kingdom
Royal Devon & Exeter Hospital, Exeter, Devon, United Kingdom
Derriford Hospital, Plymouth, Devon, United Kingdom
Broomfield Hospital Chelmsford, Chelmsford, Essex, United Kingdom
Queen's Hospital, Romford, Essex, United Kingdom
Aberdeen Royal Infirmary, Aberdeen, Foresterhill, United Kingdom
Queen Alexandra Hospital, Portsmouth, Hampshire, United Kingdom
Medway Maritime Hospital, Gillingham, Kent, United Kingdom
Blackpool Victoria Hospital, Blackpool, Lancashire, United Kingdom
Royal Oldham Hospital, Manchester, Lancashire, United Kingdom
Queens Medical Centre, Nottingham, Nottinghamshire, United Kingdom
Ipswich Hospital, Ipswich, Suffolk, United Kingdom
Heart of England NHS Foundation Trust, Birmingham, West Midlands, United Kingdom
Russells Hall Hospital, Dudley, West Midlands, United Kingdom
St Bartholomew's Hospital, London, West Smithfield, United Kingdom
Bradford Royal Infirmary, Bradford, West Yorkshire, United Kingdom
St James's University Hospital, Leeds, West Yorkshire, United Kingdom
Monklands Hospital, Airdrie, , United Kingdom
Bristol Haematology and Oncology Centre, Bristol, , United Kingdom
Addenbrooke's Hospital, Cambridge, , United Kingdom
University Hospital Wales, Cardiff, , United Kingdom
Croydon University Hospital, Croydon Health Services NHS Trust, Croydon, , United Kingdom
Western General Hospital, Edinburgh, , United Kingdom
Beatson West of Scotland Cancer Centre, Glasgow, , United Kingdom
Guy's Hospital, London, , United Kingdom
King's College Hospital, London, , United Kingdom
The James Cook University Hospital, South Tees Hospitals NHS Foundation Trust, Middlesbrough, , United Kingdom
Oxford University Hospitals NHS Foundation Trust, Oxford, , United Kingdom
Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS FT, Sheffield, , United Kingdom
Royal Stoke University Hospital, Cancer Centre, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, , United Kingdom
Singleton Hospital, Swansea, , United Kingdom
Contact Details
Name: Michael Thompson, MD
Affiliation: Incyte Biosciences UK
Role: STUDY_DIRECTOR
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