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Spots Global Cancer Trial Database for Circadian Disturbances After Breast Cancer Surgery

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Circadian Disturbances After Breast Cancer Surgery

Official Title: Circadian Disturbances After Breast Cancer Surgery

Study ID: NCT01171508

Study Description

Brief Summary: The purpose of this study is to investigate circadian disturbances after breast cancer surgery by means of monitoring sleep and heart-rate variability, by measuring a metabolite of melatonin in urine and by questionnaires and a sleep-diary.

Detailed Description: An increasing number of studies have shown that circadian variation in the excretion of hormones, the sleep-wake cycle, the core body temperature, the tone of the autonomic nervous system and the activity rhythm are important both in health and disease processes. More attention is being paid towards the circadian variation in endogenous rhythms in relation to surgery and whether this can affect postoperative recovery, morbidity and mortality. Studies have been done on circadian disturbances after major and minor surgery but never in relation to breast cancer surgery. This study will investigate circadian disturbances in this specific group of patients by using Actigraphy, Polysomnography (PSG), Holter-monitoring (HRV), the primary metabolite of melatonin in urine 6-sulfatoxymelatonin (aMT6s), questionnaires and a sleep-diary.

Eligibility

Minimum Age: 30 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Herlev Hospital, Copenhagen, , Denmark

Contact Details

Name: Melissa V Hansen, MD

Affiliation: Herlev Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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