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Spots Global Cancer Trial Database for Detection of Circulating Tumor Cells in Peripheral Blood From Healthy Volunteers and Patients With Cancer

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Trial Identification

Brief Title: Detection of Circulating Tumor Cells in Peripheral Blood From Healthy Volunteers and Patients With Cancer

Official Title:

Study ID: NCT02904161

Interventions

Study Description

Brief Summary: To address the challenges of isolating and analyzing rare cells, this study aims to validate technical diagnostic instrumentation, tests, protocols and analysis to correlate the number of circulating tumor cells present in whole blood for predicting cancer prognosis and treatment efficacy. Investigators propose to enroll and follow cohorts of cancer patients. Blood samples will be collected from these patients at regular intervals as determined by their doctors. The patient's disease progression will be monitored over the lifetime of this study. The specific aims are to isolate, enumerate and analyze the number of circulating tumor cells (CTCs) in patient blood using chip-based sorting, filtration and imaging techniques. Investigators will also use this study to optimize diagnostic instrumentation, test protocols and downstream CTC analysis. Investigators may also correlate the results of these tests with the prognosis of the patients as well as any clinical evidence (e.g. from radiological imaging scans). While investigators focus on prognosis in this study, these correlated tests potentially may also be valuable in future studies for early diagnosis and monitoring of cancer.

Detailed Description:

Keywords

Eligibility

Minimum Age: 20 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Mackay Memorial Hospital, Taipei, , Taiwan

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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