Spots Global Cancer Trial Database for Circulatory Function in Laparoscopic Radical Cystectomy for Bladder Cancer

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Trial Identification

Brief Title: Circulatory Function in Laparoscopic Radical Cystectomy for Bladder Cancer

Official Title: Preliminary Study on the Changes of Perioperative Circulatory Function in Patients Undergoing Laparoscopic Radical Cystectomy for Bladder Cancer

Study ID: NCT03892031

Conditions

Circulatory Function

Laparoscopic Radical Cystectomy for Bladder Cancer

Interventions

Study Description

Brief Summary: To optimize the perioperative management of patients undergoing laparoscopic radical cystectomy(LPC) for bladder cancer through observation of perioperative changes of Brain Natriuretic Peptide(BNP), stroke volume variation(SVV), central venous pressure(CVP) and the use of transthoracic echocardiography(TTE).

Detailed Description: Long term pneumoperitoneum and steep trendelenburg in LPC for bladder cancer influence perioperative circulatory function, resulting in a series of pathophysiological changes. BNP is of high sensitivity and specificity in the evaluation of cardiac function. SVV and CVP are dynamic and static indices to predict fluid responsiveness. TTE is a good indicator of volume and cardiac function.Thus, we conducted the trial to assess the perioperative circulatory function in patients undergoing LPC. We hypothesized that long term pneumoperitoneum and steep trendelenburg in LPC for bladder cancer would increase perioperative blood volume and influence cardiac function.