Spots Global Cancer Trial Database for Phase II Study of Oral Panobinostat in Adult Participants With Relapsed/Refractory Classical Hodgkin's Lymphoma
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Trial Identification
Brief Title: Phase II Study of Oral Panobinostat in Adult Participants With Relapsed/Refractory Classical Hodgkin's Lymphoma
Official Title: A Phase II Study of Oral Panobinostat in Adult Patients With Relapsed/Refractory Classical Hodgkins Lymphoma After High-dose Chemotherapy With Autologous Stem Cell Transplant
Study ID: NCT00742027
Conditions
Interventions
Study Description
Brief Summary: This study evaluated the efficacy of oral panobinostat in participants with refractory/relapsed classical Hodgkins lymphoma (HL) who have received prior treatment with high dose chemotherapy and autologous stem cell transplant. Safety of panobinostat also was assessed. Other markers that may correlate with efficacy or safety were explored.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
City of Hope National Medical Center Dept.ofCityofHopeMedicalCtr(2), Duarte, California, United States
Emory University School of Medicine/Winship Cancer Institute Dept. of Hematology (2), Atlanta, Georgia, United States
Georgia Regents University Cancer Clinical Research Unit, Augusta, Georgia, United States
Rush University Medical Center Divisionof Hem/Onc Research(2), Chicago, Illinois, United States
VA Maryland Health Care Dept.of GreenbaumCancerCent(5), Baltimore, Maryland, United States
Dana Farber Cancer Institute Hematology / Oncology, Boston, Massachusetts, United States
Karmanos Cancer Institute Div.of Hematology/Oncology, Detroit, Michigan, United States
Mayo Clinic - Rochester Hematology, Rochester, Minnesota, United States
University of Pennsylvania Medical Center Dept of UPenn Med Ctr (3), Philadelphia, Pennsylvania, United States
University of Texas/MD Anderson Cancer Center Dept.ofMDAndersonCancerCtr(3), Houston, Texas, United States
The Methodist Hospital Cell & Gene Therapy Clinic, Houston, Texas, United States
Cancer Therapy & Research Center / UT Health Science Center InstituteForDrugDevelopment(5), San Antonio, Texas, United States
West Virginia University/ Mary Babb Randolph Cancer Center, Morgantown, West Virginia, United States
Novartis Investigative Site, Herston, Queensland, Australia
Novartis Investigative Site, Malvern, Victoria, Australia
Novartis Investigative Site, Bruxelles, , Belgium
Novartis Investigative Site, Charleroi, , Belgium
Novartis Investigative Site, Leuven, , Belgium
Novartis Investigative Site, Rio de Janeiro, RJ, Brazil
Novartis Investigative Site, Campinas, SP, Brazil
Novartis Investigative Site, São Paulo, SP, Brazil
Novartis Investigative Site, São Paulo, SP, Brazil
Novartis Investigative Site, Dijon, , France
Novartis Investigative Site, Lille Cedex, , France
Novartis Investigative Site, Lyon Cedex, , France
Novartis Investigative Site, Marseille, , France
Novartis Investigative Site, Rennes, , France
Novartis Investigative Site, Villejuif Cedex, , France
Novartis Investigative Site, Dresden, , Germany
Novartis Investigative Site, Göttingen, , Germany
Novartis Investigative Site, Köln, , Germany
Novartis Investigative Site, Be'er Sheva, , Israel
Novartis Investigative Site, Jerusalem, , Israel
Novartis Investigative Site, Ramat Gan, , Israel
Novartis Investigative Site, Bologna, BO, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Rozzano, MI, Italy
Novartis Investigative Site, Torino, TO, Italy
Novartis Investigative Site, Udine, UD, Italy
Novartis Investigative Site, Selangor, , Malaysia
Novartis Investigative Site, Auckland, , New Zealand
Novartis Investigative Site, Singapore, , Singapore
Novartis Investigative Site, Barcelona, Cataluña, Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Withington, Greater Manchester, United Kingdom
Novartis Investigative Site, Southampton, , United Kingdom
Contact Details
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR
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