Spots Global Cancer Trial Database for A Phase 1 Study of AB521 in Renal Cell Carcinoma and Other Solid Tumors
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Trial Identification
Brief Title: A Phase 1 Study of AB521 in Renal Cell Carcinoma and Other Solid Tumors
Official Title: A Phase 1, Open-label, Dose Escalation and Dose Expansion Study, to Investigate the Safety, Tolerability, and Pharmacokinetic Profile of AB521 Monotherapy in Participants With Clear Cell Renal Cell Carcinoma and Other Solid Tumors
Study ID: NCT05536141
Interventions
Study Description
Brief Summary: The purpose of this study is to evaluate the safety and tolerability of AB521 when taken alone in participants with advanced solid tumor malignancies and clear cell renal cell carcinoma (ccRCC).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
UCLA, Santa Monica, California, United States
University of Miami, Miami, Florida, United States
University of Louisville Brown Cancer Center, Louisville, Kentucky, United States
Oschner Health, New Orleans, Louisiana, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Barbara Ann Karmanos Cancer Center, Detroit, Michigan, United States
Henry Ford Health System, Detroit, Michigan, United States
Nebraska Cancer Specialists - Oncology Hematology West PC, Omaha, Nebraska, United States
Tisch Cancer Institute, Mount Sinai Hospital, New York, New York, United States
Cleveland Clinic, Cleveland, Ohio, United States
Sarah Cannon, Nashville, Tennessee, United States
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States
South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas, United States
Seoul National University Bundang Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Severance Hospital Cancer Center, Seoul, , Korea, Republic of
Contact Details
Name: Medical Director
Affiliation: Arcus Biosciences
Role: STUDY_DIRECTOR
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