Spots Global Cancer Trial Database for A Study of Enasidenib in People With Clonal Cytopenia of Undetermined Significance
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Trial Identification
Brief Title: A Study of Enasidenib in People With Clonal Cytopenia of Undetermined Significance
Official Title: A Pilot Study of Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2
Study ID: NCT05102370
Interventions
Study Description
Brief Summary: Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve blood cell counts. The purpose of this study is to find out whether enasidenib is a safe and effective treatment for CCUS.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Mayo Clinic (Data Collection Only), Rochester, Minnesota, United States
Washington University (Data Collection and Specimen Analysis), Saint Louis, Missouri, United States
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities), Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth (All protocol activities), Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen (Limited protocol activities), Montvale, New Jersey, United States
Memorial Sloan Kettering Suffolk-Commack (Limited protocol activities), Commack, New York, United States
Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison, New York, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York, United States
Memorial Sloan Kettering Nassau (Limited protocol activities), Rockville Centre, New York, United States
Cleveland Clinic (Data Collection Only), Cleveland, Ohio, United States
Ohio State University (Data Collection Only), Columbus, Ohio, United States
Oregon Health & Science University (Data Collection Only), Portland, Oregon, United States
Contact Details
Name: Eytan Stein, MD
Affiliation: Memorial Sloan Kettering Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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