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Brief Title: Gemcitabine, Paclitaxel and Oxaliplatin (GemPOx)
Official Title: A Phase II Clinical Trial of Induction Chemotherapy Regimen Gemcitabine, Paclitaxel and Oxaliplatin (GemPOx) Followed by a Single Cycle of High Dose Chemotherapy (HDC) and Autologous Hematopoietic Stem Cell Rescue (AuHSCR) for Patients With Recurrent or Progressive Intracranial Germ Cell Tumors
Study ID: NCT01270724
Brief Summary: This study will look to see how well patients with relapsed or recurrent intracranial germ cell tumors respond to the new combination of chemotherapy (in induction)of Gemcitabine, Paclitaxel and Oxaliplatin (GemPOx) followed by consolidation chemotherapy and autologous stem cell rescue.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Phoenix Children's Hospital, Phoenix, Arizona, United States
Children's Hospital Los Angeles, Los Angeles, California, United States
New York University Langone Medical Center, New York, New York, United States
Nationwide Children's Hospital, Columbus, Ohio, United States
The Ohio State University Wexner Medical Center_The James Comprehensive Cancer Center, Columbus, Ohio, United States
Name: Randal Olshefski, MD
Affiliation: Nationwide Children's Hospital
Role: PRINCIPAL_INVESTIGATOR